Coagulation/Special Populations Flashcards
Warfarin + Amiodarone interaction, what happens?
Increased INR, decrease dose of warfarin
INR is between 4.5 - 10, but there is no bleed, what do you do?
Hold doses of warfarin, start again at lower dose
INR > 10, but no bleed, what do you do?
Give PO Vit. K + resume warfarin at lower dose
Major bleed regardless of INR, what do you do?
Hold warfarin, give IV Vit. K + Kcentra
INR < 4.5 and no bleed, what do you do?
Reduce or skip warfarin dose
Which anticoagulant cant be used in patients with CrCl > 95?
Edoxaban
Which anti-convulsant can cause weight loss?
Topirimate
Which weight loss drug should only be used for short term?
Phentermine (up to 12 weeks)
Generic of Xenical?
Orlistat
Generic of Adipex-P?
Phentermine
BBW of IVIG?
Renal dysfunction (more likely with products stabilized w/ sucrose)
BBW of vasopressors?
All vasopressors are vesicants, treat extravasation w/ phentolamine
MOA of dopamine?
1-4mcg/kg/min = Dopamine 1 agonist
5-10mcg/kg/min = beta 1 agonist
10-20 mcg/kg/min = alpha 1 agonist
Thiopurines (azathioprine, mercaptopurine) are used in (UC/CD)?
Both
MTX is used in (UC/CD)?
CD only