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NAPLEX > Cardio > Flashcards

Cardio Flashcards

1
Q

What is the LDL equation?

A

LDL = TC - HDL - TG/5

Equation can’t be used when TG > 400

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2
Q

High intensity statins are indicated for whom?

A
  1. LDL ≥ 190

2. LDL 70 - 189 AND diabetes AND aged 40-75

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3
Q

High intensity Lipitor dose?

A

40-80mg

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4
Q

Generic of Crestor?

A

Rosuvastatin

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5
Q

Generic of Lipitor?

A

Atorvastatin

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6
Q

High intensity Crestor dose?

A

20-40mg

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7
Q

Statin interactions?

A

Niacin and fibrates (specifically gemfibrozil)

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8
Q

Generic of Zocor?

A

Simvastatin

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9
Q

2 statins have many drug interactions, which ones are they?

A

Simvastatin + lovastatin; with grapefruit, protease inhibitors, azoles, macrolides (except zithromax) and amiodarone

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10
Q

Which cholesterol lowering drug can increase uric acid and BG?

A

Niacin

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11
Q

Which cholesterol drug can increase LDL?

A

Fish oil (not with Vascepa (Icosapent ethyl) though)

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12
Q

MOA of fibrates

A

PPAR alpha activators

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13
Q

Niacin MOA

A

Decreased hepatic synthesis of VLDL

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14
Q

Zetia MOA

A

Inhibits cholesterol in small intestines

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15
Q

When to start Tx for HTN?

A
  1. ≥140 or ≥90

2. 130-139 or 80-89 AND ASCVD risk ≥10% or CVD

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16
Q

Initial drug selection for HTN?

A
  1. Non blacks = thiazide, CCB, ACEi or ARBs

2. Blacks = thiazide or CCB

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17
Q

Generic of Lotrel?

A

Amlodipine / Benazepril

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18
Q

Generic of Microzide?

A

HCTZ

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19
Q

What are the Beta-1 selective BB?

A

Atenolol, Esmolol, Metoprolol

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20
Q

HTN and Pregnancy?

A

Use labetalol, Nifedipine ER, or methyldopa

21
Q

Which BB are taken with food?

A

Metoprolol and carvedilol

22
Q

Ziac generic?

A

Bisoprolol / HCTZ

23
Q

Unique AE of olmesartan?

A

Sprue-like enteropathy

24
Q

Brand of olmesartan?

A

Benicar

25
Q

Which PPIs should be avoided with Plavix?

A

Omeprazole + esomeprazole

26
Q

Brand of omeprazole?

A

Prilosec

27
Q

Brand of esomeprazole?

A

Nexium

28
Q

General Antianginal Tx?

A

Beta - blockers, CCB, Nitrates, and Ranolazine

29
Q

Brand of Ranolazine?

A

Ranexa

30
Q

Ranolazine AE?

A

QT prolongation

31
Q

ACS general Tx plan?

A

MONA-GAP–BA

32
Q

Brand of Ticagrelor?

A

Brillanta

33
Q

C/I of Prasugrel?

A

Serious bleeds or h/x of TIA or stroke

34
Q

C/I of Ticagrelor?

A

Just bleeds

35
Q

Which P2Y12i should be stopped 7 days prior to surgery?

A

Prasugrel, the others are 5 days

36
Q

Which P2Y12i should not have ASA exceed 100mg?

A

Ticagrelor

37
Q

Therapeutic range of digoxin in CHF?

A

0.5 - 0.9

38
Q

Which meds used in CHF dont improve survival?

A

Ivabradine + digoxin

39
Q

Generic of Vasotec

A

Enalapril

40
Q

What is the difference between thiazides and loop diuretics in terms of which electrolytes are affected?

A

Loop = K, Mg, Na, Cl, and Ca are all lowered

Thiazides = Same, except Ca is increased

41
Q

What are the class 2 anti-arrhythmics?

A

Beta Blockers

42
Q

What are the class 1c anti-arrhythmics?

A

Flecainide + Propafenone

43
Q

What are the class 4 anti-arrhythmics?

A

Verapamil + Diltiazem

44
Q

What are the class 1b anti-arrhythmics?

A

Lidocaine + Mexiletine

45
Q

What are the class 1a anti-arrhythmics?

A

Disopyramide, Qunidine, Procainamide

46
Q

Therapeutic range of digoxin for A.Fib?

A

0.8 - 2.0

47
Q

What are the class 3 anti-arrhythmics?

A

Amiodarone, Sotalol

48
Q

What is nimodipine used for?

A

Used orally to prevent vasospams in acute subarachnoid hemorrhages

NAPLEX (9 decks)

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