Oncology

Question 1

Chemo-man, what causes neurotoxicity?

Answer 1

N from the top of head = -mustines

Question 2

Chemo-man, what causes hemorrhagic cystitis?

Answer 2

IP on the groin = ifosfamide + cyclophosphamide

Question 3

Chemo-man, what causes mucositis?

Answer 3

M on the mouth = Methotrexate

Question 4

Chemo-man, what causes cardio toxicity?

Answer 4

D on the heart = doxorubicin

Question 5

Chemo-man, what causes peripheral toxicity?

Answer 5

V/T on the hands = vincas + -taxels

Question 6

Chemo-man, what causes pulmonary fibrosis?

Answer 6

B on the chest = bleomycin, busulfan, -mustines

Question 7

Chemo-man, what causes nephrotoxicity?

Answer 7

C on the kidneys = cisplatin + carboplatin

Question 8

Chemo-man, what causes ototoxicity?

Answer 8

C also on the ears too = Cisplatin and Carboplatin

Question 9

Lifetime cumulative dose of doxorubicin is..?

Answer 9

450-550mg/m²

Question 10

Which drug is given with doxorubicin prophylactically?

Answer 10

Dexrazoxane

Question 11

Which drug is given with Cisplatin prophylactically?

Answer 11

Amifostine (Ethyol) to reduce risk of nephroxicity

Question 12

What is the max dose of cisplatin that can be given?

Answer 12

100 mg/m²/cycle

Question 13

Which drug is given with ifosfamide (sometimes with cyclophosphamide) prophylactically?

Answer 13

Mesna (Mesnex) + hydration

Question 14

Which chemo is associated with >90% emetic risk drug?

Answer 14

The C’s : Cisplatin, cyclophosphamide, carmustine, and doxorubicin + ifosphamide