HIV Flashcards
Generic of Descovy
Emtricitabine / Tenofovir AF
Generic of Isentress
Raltegravir
Drugs ending in -gravir are classified as what?
INSTIs
What class do Emtricitabine and Tenofovir belong in?
NRTIs
AE specific to Emtricitabine?
Hyperpigmentation of palms of hands + soles of feet
AE specific to NRTIs as a whole?
Lactic acidosis, steatosis, and increased LFTs
Brand of Raltegravir?
Isentress
Brand of Emtricitabine / Tenofovir AF?
Descovy
Brand of Embtricitabine / Tenofovir DF
Truvada
AE of INSTIs as a whole?
HA, weight gain, risk of depression and suicidal ideation in pre-existing psych conditions
AE of raltegravir specifically?
⇡ CPK and rhabdo
Brand of dolutegravir?
Tivicay
What class of drugs does dolutegravir belong to?
INSTI, same as raltegravir
AE specifically for dolutegravir?
Hypersensitivity rxns, neural tube defects (but is okay to take in pregnant women), and ⇡ CPK
Special DDI with INSTIs are…
Separate them from polyvalent cations by 2hrs before or 6 hours after