Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

DERM (Dermatology) > Psoriasis > Flashcards

Psoriasis Flashcards

You may prefer our related Brainscape-certified flashcards:
Dermatology Board Prep flashcards
1
Q

What is Psoriasis?

A

A chronic autoimmune condition that causes recurrent symptoms of Psoriatic Skin Lesions.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Differential Diagnoses of Scaly Rash (7).

A
  1. Pityriasis Rosea.
  2. Tinea.
  3. Seborrheic Dermatitis.
  4. Bowen’s Disease.
  5. Discoid Eczema.
  6. Mycosis Fungoides.
  7. Discoid Lupus.
  8. Scabies.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Pathophysiology of Psoriasis.

A

Rapid generation of new skin cells, resulting in an abnormal buildup and thickening of skin in those areas.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Types of Psoriasis (4).

A
  1. Plaque Psoriasis (Adults : Commonest).
  2. Guttate Psoriasis (Children : Commonest).
  3. Pustular Psoriasis.
  4. Erythrodermic Psoriasis.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Key Features of Plaque Psoriasis (2).

A
  1. Thickened Erythematous Plaques with Silver Scales.

2. Extensor Surfaces and Scalp.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Key Features of Guttate Psoriasis (5).

A
  1. Small Raised Mildly Erythrematous and Slightly Scaly Papules (Teardrop).
  2. Trunk and Limbs.
  3. Over time, papule turn into Plaques.
  4. Triggered by Streptococcal Throat Infection, Stress or Medications.
  5. Resolves spontaneously within 3-4 months.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Key Features of Pustular Psoriasis (4).

A
  1. Rare Severe Form.
  2. Pustules form under areas of erythematous skin.
  3. Pus is not infectious.
  4. Systemically Unwell; Medical Emergency; Admission.
  5. Soles and Palms.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Key Features of Erythrodermic Psoriasis (4).

A
  1. Rare Severe Form.
  2. Extensive Erythematous Inflamed Areas Covering Most Skin.
  3. Exfoliation - Skin comes away in large patches resulting in raw exposed areas.
  4. Medical Emergency - Admission.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Clinical Features of Psoriasis (2).

A
  1. Dry, Flaky, Scaly and faintly Erythematous Skin Lesions.

2. Raised and Rough Plaques over Extensor Surfaces and Scalp.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Specific Signs of Psoriasis (3).

A
  1. Auspitz Sign (Small Points of Bleeding where Plaques are Scraped Off).
  2. Koebner Phenomenon (Development of Psoriasis to Areas Affected by Trauma).
  3. Residual Pigmentation (of skin after lesions resolve).
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Key Features of Nail Psoriasis (5).

A
  1. Nail Pitting.
  2. Nail Thickening.
  3. Nail Discolouration.
  4. Nail Ridging.
  5. Onycholysis (Separation of Nail from Nail Bed).
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Exacerbating Factors of Psoriasis (4).

A
  1. Trauma.
  2. Alcohol.
  3. Drugs.
  4. Withdrawal of Systemic Steroids.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Drugs that Exacerbate Psoriasis (6).

A
  1. B-Blockers.
  2. Lithium.
  3. Antimalarials (Chloroquine, Hydrochloroquine).
  4. NSAIDs.
  5. ACE Inhibitors.
  6. Infliximab.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Investigations of Psoriasis..

A

Diagnosis - Clinical.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Main Lines of Management of Psoriasis (3).

A
  1. Topical Steroids + Topical Calcipotriol (Vitamin D Analogue) Once Daily for 4 weeks.
  2. Vitamin D Analogue BD after 8 weeks.

1st Line : A Potent Corticosteroid (AM) + Vitamin D Analogue (PM) Applied Once Daily for 4 weeks.
2nd Line : After 8 Weeks - Vitamin D Analogue Twice Daily.
3rd Line : After 8-12 Weeks : Potent Corticosteroid Applied Twice Daily for 4 weeks (or Coal Tar Preparation).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Other Medical Options in Management of Psoriasis (2).

A
  1. Topical Dithranol.

2. Topical Calcineurin Inhibitor - Tacrolimus (ADULTS).

17
Q

Systemic Management of Psoriasis (4).

A

1st Line : Oral Methotrexate.

  1. Ciclosporin.
  2. Systemic Retinoids.
  3. Biologics.
18
Q

Phototherapy of Psoriasis (3).

A
  1. Treatment of Choice : 3x Weekly - Narrowband UVB Light.
  2. Photochemotherapy - PUVA (Psoralen + UV A Light).
  3. Adverse Effects : Skin Ageing, SCC.
19
Q

How does Dithranol work? (3)

A
  1. Inhibits DNA Synthesis.
  2. Wash off after 30 minutes.
  3. Adverse Effects : Burning and Staining.
20
Q

How do Vitamin D Analogues work? (5)

A
  1. Reduce cell division and differentiation to reduce epidermal proliferation.
  2. Can be used long-term unlike steroids.
  3. No staining or smell like coal tar or dithranol.
  4. Reduce scale and thickness of plaques but not erythema.
  5. Avoid in pregnancy.
21
Q

Steroid Mangement in Psoriasis (3).

A
  1. Adverse Effects : Skin Atrophy, Striae, Rebound Symptoms.
  2. Do Not Use More than 1-2 weeks/months.
  3. 4 week break before starting another course of topical steroids.
22
Q

Adverse Effects of Ciclosporin (5).

A

5Hs :

  1. Hypertrophy (Gum).
  2. Hypertrichosis.
  3. Hypertension.
  4. Hyperkalaemia.
  5. Hyperglycaemia (Diabetes).
23
Q

Associated Diseases with Psoriasis (5).

A
  1. Arthritis.
  2. CVD.
  3. Metabolic Syndrome.
  4. VTE.
  5. Psychological Distress.

DERM (Dermatology) (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions