Pseudocholinesterase deficiency Flashcards
1
Q
What populations does it occur more commonly in?
A
Persian Jewish community
Alaska natives
2
Q
What drugs should be avoided?
A
Donepexil
Galantamine
Procaine (novocain)
Suxamethonium
Pilocarpine
3
Q
What are the signs and symptoms of it?
A
Prolonged cholinergic effects
Excessive cholinergic activity - N+V, diarrhoea, bradycardia, hypersalivation, muscle cramps
CNS effects - confusion and dizziness, headaches
Cholinergic crisis
4
Q
What are signs of a cholinergic crisis
A
Extreme muscle weakness
Respiratory depression
