HIV

Question 1

WHat cells are depleted in HIV?

Answer 1

CD4+ T cells

Question 2

What are the three stages?

Answer 2

Acute seroconversion
Asymptomatic infection
AIDS

Question 3

Give examples of non-nucleoside reverse-transcriptase inhibitors

Answer 3

efavirenz
nevirapine

Question 4

Give examples of nucleoside reverse transcriptase inhibitors

Answer 4

abacavir
didanosine

Question 5

Give examples of protease inhibitors

Answer 5

retinovir
indinavir

Question 6

What is the most prevalent psych illness in HIV?

Answer 6

Depression

Question 7

Which HIV medication can cause depression?

Answer 7

efavirenz

Question 8

What are early indicators of HIV associated neurocognitive disorder?

Answer 8

1. Impairments in psychomotor function - slowed movements, impaired coordination and gait
2. Impairments in simple and divided attention and concentration
3. Impairments in mental agility and menta lflexibility

Question 9

What is well preserved in HAND?

Answer 9

Language

Question 10

what personality changes are seen in HAND

Answer 10

Apathy
Irritability
Inertia

Question 11

What can be seen later in HAND?

Answer 11

Hyperreflexia
Dysdiadochokinesia
Ocular pursuit abnormalities
Myoclonus
Frontal lobe signs

Question 12

What is treatment of psychosis in HIV?

Answer 12

Atypical APs

Question 13

What should be avoided in delirium in HIV?

Answer 13

Benzos

Question 14

What is treatment of depression in HIV?

Answer 14

SSRIs - especially escitalopram /citalopram

Question 15

What is first line for anxiety in HIV?

Answer 15

SSRIs

Question 16

What is preferred treatment for bipolar ?

Answer 16

Valproate