Protein Trafficking Flashcards

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1
Q

Membrane-enclosed Organelles (7)

A
  1. Nucleus
  2. ER
  3. Golgi apparatus
  4. Lysosomes
  5. Endosomes
  6. Mitochondria
  7. Peroxisomes
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2
Q

contains many metabolic pathways, protein synthesis, cytoskeleton

A

cytosol

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3
Q

contains main genome, DNA and RNA synthesis

A

nucleus

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4
Q

synthesis of most lipids, synthesis of proteins for distribution to plasma membrane

A

ER

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5
Q

modification, sorting, and packaging of proteins and lipids for delivery

A

Golgi apparatus

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6
Q

intracellular degradation

A

lysosomes

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7
Q

sorting of endocytosed material

A

endosomes

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8
Q

ATP synthesis by oxidative phosphorylation

A

mitochondria

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9
Q

ATP synthesis and carbon fixation by photosynthesis

A

chloroplasts

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10
Q

oxidation of toxic molecules

A

peroxisomes

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11
Q

What did nuclear membranes and the ER evolve from?

A

invaginations of the plasma membrane

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12
Q

What did the mitochondria originate from?

A

an engulfed prokaryotic cell

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13
Q

3 mechanisms to import proteins

A
  1. Transport thru nuclear pores
  2. Transport across membranes
  3. Transport by vesicles
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14
Q

Signal sequences can direct proteins towards their direction (T of F)

A

True

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15
Q

forms a gate that selects which proteins can enter and exit the nucleus

A

nuclear pore

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16
Q

What does the energy supplied by GTP hydrolysis drive?

A

nuclear transport

17
Q

Mitochondria precursor proteins are folded during import (T or F)

A

False, unfolded

18
Q

What do membrane vesicles do?

A

They bud from one membrane and fuse with another to transport proteins to or from the plasma membrane

19
Q

What do clathin-coated vesicles transport?

A

cargo molecules

20
Q

Chaperones prevents misfolded or damaged proteins from leaving the ER (T or F)

A

True