Protein Synthesis Flashcards

1
Q

Process of protein synthesis where mRNA is synthesized from a DNA template in order to transfer info from DNA to RNA. It occurs in the nucleus

A

Transcription

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2
Q

Process of protein synthesis where a protein is synthesized off of an mRNA template. Occurs in the cytoplasm. Uses mRNA, tRNA, and ribosome

A

Translation

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3
Q

During transcription, a DNA molecule is unzipped and the nitrogen bases (AT CG) are exposed. what synthesizes mRNA from the unzipped areas with complimentary base pairing?

A

RNA Polymerase

A:U
C:G

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4
Q

Three sequential bases of a synthesized mRNA which code for an amino acid are called

A

Codons

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5
Q

The synthesized product of transcription is actually
a pre-mRNA which is subsequently edited or
shortened to form the mRNA which will be used for
transcription

The non informational regions that are edited out

The informational regions that are left in and spliced together

A

Introns

Exons

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6
Q

Where does mRNA leave the nucleus through to enter the cytoplasm?

A

Nuclear Pores

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7
Q

The process of protein synthesis where upon arrival of the mRNA into the cytoplasm,
ribosomes (rRNA and protein organelles) will bind with the mRNA to begin it…

A

Translation

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8
Q

Name the 3 sites of ribosomes

A

P-Site
A-Site
E-Site

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9
Q

The site of a ribosome that binds with the tRNA carrying amino acid (1st)

A

P-site

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10
Q

The site of a ribosome that binds with a tRNA carrying amino acid (2nd)

A

A-site

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11
Q

The site of a ribosome from where empty tRNA is released

A

E-site

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12
Q

Synthesized separately off of DNA molecule and are “ready and waiting” in the cytoplasm when protein synthesis occurs

A

tRNA

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13
Q

What do tRNAs have on each end?

What binds with codon on mRNA?

A

Amino Acid and Anti-Codon

Anti-codon (duh)

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14
Q

What happens to the amino acids when the tRNAs bind with the mRNA?

A

They form a peptide bond with eachother

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15
Q

The ribosome translocates the two tRNAs to the next site, The initiator tRNA goes to the E site and then exits, while the second tRNA goes to the P site. The ribosome also slides the mRNA to the next codon. A third tRNA will bind at that codon

A

!!

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16
Q

This process will continue and a peptide bond will be formed between the newly arrived amino acid (AA3) on the new tRNA and the previously formed dipeptide as shown.

A

!!

17
Q

This process will continue as before with new tRNAs entering. The peptide will grow to the length specified by the length of the mRNA. At the end of the mRNA will be a STOP codon which will dictate that translation should cease.

A

!!

18
Q

multiple ribosomes can bind
with mRNA; allows formation of multiple copies of
a specific protein from one template

A

Polyribosome

19
Q

Increase in the number of proliferation of cells

Increase in cell size

Loss of cell size

A

Hyperplasia

Hypertrophy

Atrophy