Protein Metabolism Flashcards
Professor Madura
______ _____ is used in both the Urea cycle and the Aminotransferase reaction
Pyridoxal Phosphate
Dopamine, Epi, NE, THyroxine, and Melanin all have a _____ amino acid precursor
Tyrosine
Alanine’s non-amino pair is ______
Pyruvate
In SAM creation, the dynamics revolve around one bonding pair, however in Tetrahydrofolate dynamics, it is centered around _____ Nitrogen bonds.
2
Tyrosine is non-essential, unless _____ becomes limited.
Phenylalanine
Glutamate is the precursor for ______, a key allosteric activator of the Urea Cycle
N-acetylglutamate
In a vitamin B12 deficiency, Homocysteine and 5-_____ accumulate
Methyltetrahydrofolate
Oxaloacetate’s amino pair is _____
Aspartate
Homocystenine can be converted to ____ via Pyridoxal PHosphate
Cysteiene
The co-factor needed for Trans-amination reactions is ______ _____, a derivative of Vitamin B6
Pyridoxal Phosphate
An alternate use for Methionine is to attach a transferrable methyl group with the enzyme _______. This is used for RNA, DNA, Epi, choline, and melatonin.
S-adenosyl Methionine Synthase
Tetrahydrobiopterin is needed to convert Phenylalanine into ____ and Tyrosine into DOPA
Tyrosine
The two Ketogenic amino acids _____ and _____ yield Acetoacetate
Leucine and Lysine
3 co-factors needed to go from NE to E
- SAM
- B12
- Folate
Alpha-Keto-glutarate’s amino pair is ______
Glutamate
Aspartate’s non-amino pair is _____
Oxaloacetate
Glutaminase, Asparaginase, Arginase, and Carbamoyl Phosphate Synthetase I are enzymes that are exclusively found in the _____
Liver
Serotonin, Melatonin, and Niacin (B1) all derive from the amino acid _____
Tryptophan
GABA, Histamine, and Serotonin all undergo a _____ reaction to be created
Decarboxylation
Blue diaper syndrome is caused by a failure to absorb _____ in the intestine
Tryptophan
Most Alpha amino groups are transferred to ______
alpha-ketoglutarate
Homocysteine can be methylated to restore _____ with the cofactor Vitamin _____
- Methionine
- B12
Glutamate’s non-amino pair is ________
Alpha-Keto-glutarate
____ is the RLS in nitrogen excretion, and is regulated via positive regulation with N-Acetyl Glutamate
CPS-1