Protein Metabolism

Question 1

______ _____ is used in both the Urea cycle and the Aminotransferase reaction

Answer 1

Pyridoxal Phosphate

Question 2

Dopamine, Epi, NE, THyroxine, and Melanin all have a _____ amino acid precursor

Answer 2

Tyrosine

Question 3

Alanine’s non-amino pair is ______

Answer 3

Pyruvate

Question 4

In SAM creation, the dynamics revolve around one bonding pair, however in Tetrahydrofolate dynamics, it is centered around _____ Nitrogen bonds.

Answer 4

2

Question 5

Tyrosine is non-essential, unless _____ becomes limited.

Answer 5

Phenylalanine

Question 6

Glutamate is the precursor for ______, a key allosteric activator of the Urea Cycle

Answer 6

N-acetylglutamate

Question 7

In a vitamin B12 deficiency, Homocysteine and 5-_____ accumulate

Answer 7

Methyltetrahydrofolate

Question 8

Oxaloacetate’s amino pair is _____

Answer 8

Aspartate

Question 9

Homocystenine can be converted to ____ via Pyridoxal PHosphate

Answer 9

Cysteiene

Question 10

The co-factor needed for Trans-amination reactions is ______ _____, a derivative of Vitamin B6

Answer 10

Pyridoxal Phosphate

Question 11

An alternate use for Methionine is to attach a transferrable methyl group with the enzyme _______. This is used for RNA, DNA, Epi, choline, and melatonin.

Answer 11

S-adenosyl Methionine Synthase

Question 12

Tetrahydrobiopterin is needed to convert Phenylalanine into ____ and Tyrosine into DOPA

Answer 12

Tyrosine

Question 13

The two Ketogenic amino acids _____ and _____ yield Acetoacetate

Answer 13

Leucine and Lysine

Question 14

3 co-factors needed to go from NE to E

Answer 14

1. SAM
2. B12
3. Folate

Question 15

Alpha-Keto-glutarate’s amino pair is ______

Answer 15

Glutamate

Question 16

Aspartate’s non-amino pair is _____

Answer 16

Oxaloacetate

Question 17

Glutaminase, Asparaginase, Arginase, and Carbamoyl Phosphate Synthetase I are enzymes that are exclusively found in the _____

Answer 17

Liver

Question 18

Serotonin, Melatonin, and Niacin (B1) all derive from the amino acid _____

Answer 18

Tryptophan

Question 19

GABA, Histamine, and Serotonin all undergo a _____ reaction to be created

Answer 19

Decarboxylation

Question 20

Blue diaper syndrome is caused by a failure to absorb _____ in the intestine

Answer 20

Tryptophan

Question 21

Most Alpha amino groups are transferred to ______

Answer 21

alpha-ketoglutarate

Question 22

Homocysteine can be methylated to restore _____ with the cofactor Vitamin _____

Answer 22

• Methionine

- B12

Question 23

Glutamate’s non-amino pair is ________

Answer 23

Alpha-Keto-glutarate

Question 24

____ is the RLS in nitrogen excretion, and is regulated via positive regulation with N-Acetyl Glutamate

Answer 24

CPS-1

Question 25

All Three Aromatic Amino Acid Hydroxylases require _____

Answer 25

Tetrahydrobiopterin

Question 26

Cysteine is non-essential, unless _____ becomes limited

Answer 26

Methionine

Question 27

Pyruvate’s amino pair is _____

Answer 27

Alanine

Question 28

Low levels of dopamine cause _____, whereas high levels are associated with _____

Answer 28

• Parkinson’s

- Schizophrenia