Protease inhibitors Flashcards
What are protease inhibitors primarily used for?
Protease inhibitors are primarily used in the treatment of HIV/AIDS.
True or False: Protease inhibitors work by inhibiting the action of the protease enzyme.
True
Name one common protease inhibitor.
Ritonavir
What is the mechanism of action of protease inhibitors?
Protease inhibitors block the protease enzyme, preventing viral replication.
Fill in the blank: Protease inhibitors are often used in combination with ________ for enhanced effectiveness.
nucleoside reverse transcriptase inhibitors (NRTIs)
What are common routes of administration for protease inhibitors?
Oral administration is the most common route.
List one adverse effect of protease inhibitors.
Nausea
True or False: Protease inhibitors can cause liver toxicity.
True
What should nurses monitor in patients taking protease inhibitors?
Liver function tests and signs of adverse effects.
Which protease inhibitor is known for its use in low doses for boosting other antiretroviral medications?
Ritonavir
Fill in the blank: Patients on protease inhibitors may require ________ adjustments due to drug interactions.
dose
What is a key nursing consideration when administering protease inhibitors?
Educating the patient about potential drug interactions.
True or False: All protease inhibitors are taken with food to improve absorption.
False
What is the importance of adherence to protease inhibitor therapy?
Adherence is crucial to prevent viral resistance.
List two common side effects associated with protease inhibitors.
Diarrhea and headache
What is the effect of protease inhibitors on lipid levels?
They can cause increased triglycerides and cholesterol levels.
True or False: Patients should avoid grapefruit juice while taking protease inhibitors.
True
What is the role of the nurse in managing a patient on protease inhibitors?
To provide education and monitor for side effects and drug interactions.
Fill in the blank: Protease inhibitors may interact with ________ medications.
anticoagulant
What is a common contraindication for protease inhibitors?
Severe liver disease
Name one protease inhibitor that is used in pediatric patients.
Lopinavir
True or False: Protease inhibitors can be used as a single therapy for HIV.
False
What is the recommended action if a patient misses a dose of a protease inhibitor?
Take the missed dose as soon as remembered unless it’s close to the next dose.
What should be assessed before starting a patient on protease inhibitors?
Baseline liver function and potential drug interactions.
What is the significance of the ‘boosting’ effect in protease inhibitors?
Boosting increases the effectiveness of other antiretrovirals by enhancing their levels.
Fill in the blank: ________ is a common combination therapy with protease inhibitors.
NRTIs
