Entry Inhibitors Medication Flashcards

1
Q
A
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2
Q

What are Entry Inhibitors primarily used for?

A

Entry Inhibitors are primarily used for the treatment of HIV.

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3
Q

True or False: Entry Inhibitors prevent the virus from entering the host cell.

A

True

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4
Q

Name one class of Entry Inhibitors.

A

Fusion inhibitors.

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5
Q

What is the mechanism of action for Entry Inhibitors?

A

Entry Inhibitors block the virus from entering human cells.

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6
Q

Fill in the blank: One example of an Entry Inhibitor is ______.

A

Enfuvirtide.

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7
Q

List one common adverse effect of Entry Inhibitors.

A

Injection site reactions.

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8
Q

What route of administration is commonly used for Entry Inhibitors?

A

Subcutaneous injection.

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9
Q

True or False: Entry Inhibitors can be taken orally.

A

False

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10
Q

What should be monitored in patients taking Entry Inhibitors?

A

Signs of infection and injection site reactions.

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11
Q

What is the brand name of the Entry Inhibitor Maraviroc?

A

Selzentry.

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12
Q

True or False: Entry Inhibitors are effective against all strains of HIV.

A

False

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13
Q

What is the primary nursing indication for Entry Inhibitors?

A

Assessing for adherence to therapy and monitoring for side effects.

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14
Q

Fill in the blank: Entry Inhibitors may cause ______ in some patients.

A

Allergic reactions.

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15
Q

What is the role of nursing in the administration of Entry Inhibitors?

A

Educating the patient on proper injection technique.

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16
Q

Which Entry Inhibitor requires a tropism test before use?

A

Maraviroc.

17
Q

What should patients be advised regarding the use of Entry Inhibitors?

A

To report any signs of severe allergic reactions immediately.

18
Q

True or False: Entry Inhibitors can be used in combination with other antiretroviral medications.

19
Q

What is a potential serious adverse effect of Entry Inhibitors?

A

Hepatotoxicity.

20
Q

What is the recommended frequency of administration for Enfuvirtide?

A

Twice daily.

21
Q

What is a common side effect of Maraviroc?

22
Q

Fill in the blank: Entry Inhibitors are part of the ______ class of antiretroviral therapy.

A

HIV entry inhibitor.

23
Q

What is the importance of patient education regarding Entry Inhibitors?

A

To ensure adherence and understand potential side effects.

24
Q

What type of reaction is common at the injection site for Enfuvirtide?

A

Erythema and pain.

25
Q

True or False: Entry Inhibitors can be used as a first-line treatment for HIV.

26
Q

What is the purpose of a tropism test?

A

To determine the type of HIV and suitability for Maraviroc.

27
Q

What is the mechanism of action of Maraviroc?

A

It blocks the CCR5 co-receptor on CD4 cells.

28
Q

What is the tropis test?

A

A blood sample, isolating the HIV from the plasma, then analyzing its genetic material (specifically the envelope gene) to see which co-receptor (CCR5 or CXCR4) the virus primarily uses to infect cells ( there must be a high viral load before the test can be performed)