Antiretroviral Therapy Flashcards
Fusion Inhibitors, name, action, adverse effect, nursing indication, administration route
What is the name of a common fusion inhibitor medication?
Enfuvirtide
What is the primary action of fusion inhibitors?
They prevent the fusion of the virus with the host cell membrane.
True or False: Fusion inhibitors can be used as a first-line treatment for HIV.
False
What is a common route of administration for fusion inhibitors?
Subcutaneous injection
Fill in the blank: Fusion inhibitors are contraindicated in patients with a history of ______.
Hypersensitivity reactions
What should a nurse monitor after administering a fusion inhibitor?
Injection site reactions and signs of infection
Which medication is classified as a fusion inhibitor?
Enfuvirtide
What is a potential side effect of fusion inhibitors?
Injection site reactions
True or False: Fusion inhibitors are effective against all strains of HIV.
False
What is the mechanism of action of Enfuvirtide?
It binds to the gp41 subunit of the viral envelope glycoprotein.
What must be done with the reconstituted solution of Enfuvirtide?
It must be used within 24 hours.
What is the recommended frequency of administration for Enfuvirtide?
Twice daily
Fill in the blank: Patients using fusion inhibitors should be educated about the importance of ______.
Adherence to the medication regimen
What is a nursing implication when administering fusion inhibitors?
Educate the patient on proper injection techniques.
What type of patients should avoid using fusion inhibitors?
Patients with a history of severe allergic reactions to the drug.
Which laboratory tests should be monitored for patients on fusion inhibitors?
CD4 count and viral load
What is the primary goal of using fusion inhibitors in HIV treatment?
To reduce viral load and improve immune function.
True or False: Fusion inhibitors can be administered orally.
False
What is a common adverse effect associated with Enfuvirtide?
Local reactions at the injection site
What is an important consideration before administering fusion inhibitors?
Assess for any existing allergies to the medication.
Fill in the blank: Fusion inhibitors are usually combined with ______ for improved efficacy.
Other antiretroviral medications
What patient education is essential regarding the storage of Enfuvirtide?
Store in the refrigerator and do not freeze.
What is the brand name of Enfuvirtide?
Fuzeon
What should be documented after administering a fusion inhibitor?
The injection site and any adverse reactions.
True or False: Fusion inhibitors can be used in pregnant women without any concerns.
False
What is the significance of monitoring for opportunistic infections in patients taking fusion inhibitors?
They may have a weakened immune system.
