Protazoans

Question 1

What is the presenting symptom of Entamoeba histolytica?

Answer 1

Dysentery; Flask-shaped ulcers in cecum and ascending colon

Question 2

What is the pathogenesis of Entamoeba histolytica?

Answer 2

Invades cryps, burrows into lamina propia, flask shaped ulcers, may penetrate circulation, liver abscesses

Question 3

How is Entamoeba histolytica treated?

Answer 3

If asymptomatic use lodoquinol. If systemic use lodoquinol and metronidazole

Question 4

What are the presenting symptoms of Giardia? Morphology?

Answer 4

Borborygmi, flatulence, belching.

Pear shape with two nuclei bound to brush border.

Question 5

How is Giardia diagnosed? Treatment?

Answer 5

Cysts in stool; Tinadazole or Metronidazole

Question 6

What is the symptom of Cryptosporidia?

Answer 6

mild diarrhea and biliarty tract disease

Question 7

Discuss the pathogenesis of Cryptosporidia

Answer 7

Sporozites attach to brush border, engulfed, causes sodium malabsorption, chloride secretion

Question 8

What is the symptom of Cyclosporidia?

Answer 8

More severe diarrhea than Crypto

Question 9

How is Cyclosporidia diagnosed? Treated?

Answer 9

Stool culture; Bactrim.

Cipro if there’s a sulfa allergy.

Question 10

What is the presenting symptom of Clonorchiasis? Typical patient?

Answer 10

Cholangitis, cholangiocarcinoma; SE asian immigrant