Prostethic Valves Flashcards
What does this image represent?
Single tilting disk - Bork Shiley valve
What does this image represent?
Bileaflet Tilting disk
What does this image represent?
Bileaflet mechanical mitral valve
What does this image represent?
Mechanical Valve hemodynamics
What does this image represent?
What does this image represent?
Scented Bioprosthetic valve
What does this image represent?
Bioprosthetic stentless freestyle valves
What does this image represent?
Ross procedure
What does this image represent? What does the arrow point to?
- Annuloplasty ring
- The arrow Mimics MAC
What does this image represent?
TAVR (Transcatheter AV replacements)
What does this image represent?
Edge to edge repair
Why would someone have a prostatic valve?3
Implanted when the patient has hemodynamically significant valvular disease such as
- Stenosis
- Regurgitation
- Aortic dissection/ severe AI
In terms of prosthetic valves, when are valvular rings or other devices used?
When possible
What is the role of echo in prosthetic valves during pre-procedure?2
- Assess the need for repair/replacement
- Assess suitability of the type of repair/ replacement
What is the role of echo for prosthetic valves during the procedure?
May be used during transcatheter procedure to assess prosthesis placement before procedure completion
What is the role of echo post procedure for prosthetic valves?4
Assess for complications such as
1. Thrombus
2. Leakage
structural failure
3. Endocarditis
4. Dehiscence
What are the advantages of mechanical valves?3
- Durable
- Due to durability, risk for reoperation is low
- Easier surgical implantation
Why is mechanical valves durable?
- Made from biocompatible metal, plastic or cermiclike material
- Lasts 10-25 years
What is the disadvantage of mechanical valves?
- Risk of thrombus formation and pannus growth
- Valve may make an audible click
- Produces a blood flow pattern that is resistant or high flow
What is the most common disadvantage of mechanical valves?
Thrombus formation which leads to lifelong anticoagulation
Pannus growth can lead to what?
Regurgitation or stenosis
How can we size the valve to use?
Echo used in pre-procedure to determine the choice of valve size
Reported size of the valve refers to what?
Outer diameter
What is valves measured in?
Milimeters
What is a single tilting disk made of?3
- Circular ring of metal
- Disk
- Sewing ring
Single tilting disks tilt at what degree?
60 degrees
What is flow like in a single tilting disk?
Eccentric
Single tilting disks have a history of what?
Fracture and sewing ring leak
What is the most common mechanical valve?
Bileaflet tilting disk
What does the bileaflet tilting disk consist of in terms of design?
- 2 Occluders + sewing ring
- Align parallel when opening
What does bileaflet tilting disk color doppler demonstrate?3
- 3 jets
- Central flow with peripheral turbulence
The bileaflet tilting disk is a valve made to have a built in what?
Regurg
What does the built in regurg of the bileaflet tilting disk do?
- “washes” the valve
- Decrease thrombus
What does MR look like for Bileaflet tilting disk?
2 jets
Why is it frustrating to image mechanical valves?
Can be frustrating due to artifacts such as
1. Reverberation
2. Shadowing
What should we do when we image mechanical valves? 3
- Account for the motion of the occluder’s
- Use zoom/ magnifaction
- Evaluate the sewing ring
What can we do in terms of imaging mechanical valves to help assess regurgitation?
Scanning off axis
What are three types of tissue valves in terms of bioprosthetic?
- Homograft (allograft)
- Autograft
- Heterograft (xenograft)
What is a homograft?
Graft from one human to another
How common are homografts?
Rare
How do we obtain homografts?
From cadavers
How common are autografts?
Rare
What are autografts?
Graft of tissue from one site to another in the same patient
What is a heterograft?
Graft from different species?
What are examples of heterografts?
- Animal to human
- Porcine heart valve (pig)
- Bovine pericardium (cow)
How long does hetergrafts last?
5 years
What are the advantages of bioprosthetics? 3
- Anticoaguation not required, therefore may provide better quality of life
- valves do not click
- May be candidates for percutaneous valve in valve procedures at a later date
What are disadvantages of bioprosthetic valves?
- Not as durable as mechanical valves
- Prone to calcifications
Young person receiving a bioprosthetic valve may require what?
Reoperation
What happens with bioprosthetics in terms of calcifcaitons?
Stenosis with increased gradient across valve
What are components of bioprosthetic valves?
- Leaflet
- Sewing ring
+/- stents/ struts
When we image bioprosthetic valves what is the structure of the leaflets?
Trileaflet structure
In terms of imaging bioprostetic valves, what might cause an artifact?
Sewing ring and struts
What do we evaluate the sewing rings for?2
- Dehiscence
- Paravalvular leak
Between bioprosthetic valves and mechanical prosthesis, which is easier to image?
Bioprosthetic valves
What are some considerations for choice of prosthetic valves?7
- Rate of structural failure
- Effect of age very young or old
- Co-morbid conditions
- Anticoagulation with mechanical valves
- Patient preference (young, religion)
- Physical activity
- Women of childbearing age
What are 4 different types of valve replacement/ repairs?
- Ross procedure - AV replacement
- MV/TV annulplasty rings
- TAVR - transcatheter AV replacement
- Edge to edge repair
What components generally seen in a ross procedure?
Autograft + Homograft
- Patients PV and root becomes the new AV and root
- Donor PV valve and root is implanted
Who is ROSS procedure performed on?
Young people and women of childbearing years
What are some advantages of ross procedure?
- No long term anticoagulation
- Can grow with the patient
- Less immune response post operation
- Long surgery
What does Annuloplasty ring (for valve repair) treats?
Valve regurgitation such as MV and TV
What is annuloplasty ring designed to do?
- Restore the size and shape of the normal valve annulus
- Prevents recurrent dilation
Annuloplasty rings look like what?
May be full or partial rings
What is often required prior to TAVR?
Balloon valvuloplasty
What might transcatheter AV replacement lead to?
Stenosis but often leads to regurgitation
What kind of procedure is transcatheter AV replacement? TAVR
Percutaneous procedure
How is the TAVR procedure conducted?
Tissue valve mounted on balloon or self expandable stent
What is interrogated with the echo assessment of TAVR?5
- Pre-procedure measurement of the AV annulus
- # of leaflets
- Valve mobility
- AS severity
- LV fxn, hypertrophy and potential thrombus are also assessed pre-procedure
TAVI may also utilize what?
The echocardiographer to perform TEE during the procedure to evaluate prosthesis misplacement
What is edge to edge repair used for?
To treat MR
What is used for edge to edge repair?
Mitraclip
What does mitraclip?
Double orifice MV
What does the Mitra clip clamp?
AMVL + PMVL
Where does the mitra clamp attach?
In the middle avoiding any chordae
What is patient prosthesis mismatch?
Implanted valve is too small for the patients body size
What happens when the valve is too small?
- Hemodynamics consistent with prosthetic valve stenosis
- Abnormally high velocity and gradients with non-stenotic valve
What are different types of prosthetic valve dysfunctions? 4
- Structural failure
- Regurgitation
- Thromboembolic complicaitons
- Endocarditis
What type of valves is this and what is the significance of this?
This is a ball in cage valve, and it is covered in thrombus
What does this image represent?
Pannus formation on the valves
What does this image represent?
Valvular abscess on a Bioprosthetic AV
Label
What does this represent?
Valve identification chart
The EOA formula is generally only used for which valve?
AV and sometimes PV
What parameter confirms severe PI?
Reversal in the pulmonary branches
How will the heart remodel with AI?
LV dilatation
How will the heart remodel with PI?
RV dilatation
Label the image
What doe we use to measure EOA AV? And what is the formula?
Label the image
What does this image represent?
AR
What does this image represent?
Medtronic Mosaic Strut on a Bioprosthetic valve
When does structural failure normally happen with bioprosthetic valves?
Typically occurs >10 years post implantation
What does bioprosthetic failure look like?2
- Failure of leaflets to open/ close
properly due to tissue degeneration - Acute valve regurgitation (leaflet tear), usually after trauma or aging of the valve
What would be a mechanical valve fail? 3
- Valve regurgitation
- Valve stenosis
- Design flaw
What does design flaws in mechanical valves lead to?
Mechanical failure
How do we get valve stenosis with mechanical failure?
Due to pannus or thrombus formation
How do we get valve regurgitation with mechanical failure?
Due to pannus or thrombus formation
What does normal prosthetic valve regurgitation look like?
Transvalvular
What does transvalvular regurgitation look like?
- Normal “washing jets”
- Closing volume
What does closing volume look like?
As valve closes, it displaces a small volume of blood backward
What does abnormal prosthetic valve regurgitation look like? 3
- Paravalvular
- Transvalvular
- Dehiscence
What does paravalvular regurgitation look like?
Through or around the sewing ring
What does abnormal transvalvular regurgitation look like?
More than a washing jet
What does dehiscence look like? 2
- Regurgitation seen around, instead of through the valve
- Urgent finding, requires immediate attention
How does valvular dehiscence occur?
Occurs when a valve becomes detached on one side of the sewing ring, leading to rocking motion of the valve, with regurgitation slipping around the valve
What is the prognosis for valvular dehiscence?
Very serious
Where is the regurgitation with dehiscence?
Significant regurgitation around the prosthesis
How does a valvular dehiscence appear?
- Appears as instability or rocking
- Independent movement
In terms of valvular dehiscence, as part of the valve becomes detached, what happens?
More force is applied to the intact sutures, which leads to more suture detachment
What are some thromboembolic complications with prosthetic valves? 4
- Prone to thrombus formation
- U/S density of thrombi are similar to myocardium
- Thrombus may cause embolic events, Stenosis, regurgitation
- All valve replacement patients have 6 weeks of heavy anticoagulation drugs
What is pannus?
Fibrous ingrowth of tissue
Why do we have pannus formation?
Scarring respinse
Pannus formation may result in what?
Stenosis/ regurgitation
What might be required if there is a pannus formation?
TEE may be required
Why must we differentiate between pannus/ thrombus?
Thrombus treated with thrombolytics
What is the difference between pannus and thrombus in terms of occurrence?
Pannus: >12 months before malfunction
Thrombus: occurs shortly after surgery
What is the difference between pannus and thrombus in terms of size?
Pannus is smaller
What is the difference between pannus and thrombus in terms of echo texture?
Pannus is more echo dense and thrombus has more of a soft tissue appearance
What is the difference between pannus and thrombus in terms of mobility?
Pannus is fixed vs thrombus which is mobile
What is the difference between pannus and thrombus in terms of location?
Pannus usually occurs at annulus and thrombus mass extends beyond annular ring to adj structures
What is the difference between pannus and thrombus in terms of common areas?
Pannus is located more common in AV (LVOT side) and Thrombus is more common in MV
How serious is endocarditis?
Very serious clinical problem
What is endocarditis?
Vegetations on bioprosthetic valves are similar in appearance to vegetations on native valves
In terms of endocarditis and prosthetics, vegetations on mechanicals are often what? 2
Paravalvular which is
1. Irregularly shaped
2. Independently mobile structures
What is indicated if endocarditis suspected?
TEE
What might we see on the valve identification card?
- Valve size
- Type
- Physician
Who carries the identification card?
Patient
Where might you find valves chart?
In echo departments or online
In terms of values chart, once you know the patient’s valve model, what can you do?
Use these charts as a reference
What is some clinical information of patient information?
- Date of valve replacement
- Type and size
- Height/ Weight/ BSA
- Symptoms
- BP/HR
What do we look at with 2D valve imaging in terms of prosthetic valve echo?
- Motion of leaflets/ occluder
- Calcification/ abnormal echodensities
- Sewing ring integrity
What is some other 2D echo data seen with prosthetic valve echo assessment?2
- Chamber sizes (dilatation may indicate excessive regurg)
- Previous post-op studies for comparison
When we are doing an assessment of prosthetic valve echo, what do we need to do that is usually a great source of error?
Note the size of LVOT/ RVOT when comparing to previous echo
In terms of prosthetic valve doppler, when assessing prosthetic valves, we want to know if they are what?4
- Functioning adequately
- Need replacement
- Do they have significant stenosis
- Do they have significant regurgitation
All prosthetic valves have some degree of what?
Gradient by nature of their design
Almost all prosthetic valves will show what?
Normal degree of regurg
What equations will we use in prosthetic valve assessment frequently?2
- DVI (Doppler velocity index)
- EOA (effective orifice area)
What is the DVI formula and what is it?
- Simple ratio between 2 velocities or WTI
- DVI = V1/V2
What is EOA?
Essentially our valve area
What is EOA formula similar to?
Continuity equation
What are some doppler considerations of the prosthetic valve? 5
- Peak velocity and gradient
- Mean pressure gradient
- Regurgitation
- Effective orifice area
- RVSP (for back up of pressures for left heart valves)
When imaging the MV prosthetic valve for regurgitation what must we take into account?
- Mitral inflow peak velocity and VTI
- P1/2t of MV inflow
- Intensity of the MR CW doppler signal
- Systolic flow reversal in pulmonary vein
- Flow convergence size (PISA)
What is something that we must take into consideration when looking the TV valve for regurg?
- Jet density and contour (CW) of TR jet
- Systolic hepatic vein flow reversal
- RA/RV/IVC size
- Off axis views important
What are two things to remember to make valve calculations simply?
- Always obtain a CW of the highest velocities through the trace
- Always obtain a PW trace throug hthe outflow
VTI trace will give you what? 3
- Peak velocity
- Mean velocity
- VTI for ratio and continuity equation
What is the AS DVI?
Dimensionless ratio of LVOT versus AV peak velocity or VTI
When is AS DVI used?
Especially when LVOT diameter cannot be obtained
What is AS DVI used for?
Prosthetic AV
What is the normal AV:DVI?
> 0.3
What do we use to calculate stenosis in the prosthetic mitral valve area?
In terms of stenosis: of prosthetic TV, what does velocity vary with?
Respiration
What does ASE recommend for prosthetic TV stenosis? 4
- Peak E (TV inflow - PW)
- TV VTI (CW)
- P 1/2t
- Regurgitation
In terms of ASE how do we calculate PV VTI?
Trace PV VTI (CW)
Some sites will use what hethod for evaluation of bioprosthetic MV or TV Only?
P1/2T
We should never assign an LVOT of 20m, why?
There are assignable LVOTd based on BSA available on ASE website
ID cards are becoming less needed for evaluation due to what?
Similar hemodynamics between valve types