Prostate Pathology

Question 1

in what zone of the prostate does most cancer arise?

Answer 1

peripheral

Question 2

in what zone of the prostate does BPH arise?

Answer 2

transition

Question 3

what zone of the prostate is palpable upon rectal exam?

Answer 3

peripheral

Question 4

prostatitis: symptoms, acute vs. chronic

Answer 4

dysuria, frequency, urgency, low back pain

acute: bacterial
chronic: bacterial or abacterial (most common)

Question 5

BPH: ______ PSA

Answer 5

increased

Question 6

PSA: functions, what elevates it

Answer 6

protease formed by epithelial cells of prostate, keeps semen in a liquefactive form, increased by cancer, inflammation, BPH

Question 7

dx: >50 yo male, increased ALP and PSA in serum, lower back pain

Answer 7

prostatic adenocarcinoma that has metastasized to bone

Question 8

what do grading and staging of prostate cancer depend on, respectively?

Answer 8

grading: glandular architecture
staging: spread outside the prostate