Properties of Solutions Flashcards
Drugs as solutions, why?
In order to be dispersed in the body it usually has to be in a liquid form
Define solution
homogenous mixture of two or more substances
Solvent and solute
Concentration of a solution can be expressed as
Volume of solution or mass of solvent or solution
Molarity
Number of moles of solute in 1 liter of solution
mol/L
Molality
Number of moles of solute in 1000g of solvent
mol/kg
Types of solutions are based on
Particle size
Reactivity (ideal or non-ideal)
Concentration (saturation)
Types (electrolyte or non-electrolyte)
Types based on particle size
True solution, colloidal or coarse dispersions
True solutions
Particles size less than 1 nm
Homogenous
Invisible to electron microscope and to naked eyes
Colloidal Dispersion
Larger than individual ions ro molecules, but too small to settled out by gravity
Dispersed (internal phase) or continuous (dispersion medium) phases
May be solid, liquid or gas
Scatters light rays
Visible to electron microscope but can pass through filter paper
Milk
Course Dispersion
Larger than .5 micrometers
Visible to naked eye
Lotions
Suspensions
Mixed but no dissolved
Settle over time
Ideal solutions
No change in properties of the components occur when they are mixed to form the solution
No heat, shrinkage or expansion
Non ideal solutions
Heat is involved, expansion or shrinkage occur during mixing
Saturated solutions
Maximum amount of solute has been dissolved
Unsaturated solution
Solute can dissolve in the given amount of solvent at a particular temperature