Production of ATP in muscle fibers Flashcards
What is ATP used for in muscle fibers?
It is used for powering the contraction cycle and to pump calcium into the (SR).
What are the 3 ways a muscle fiber produces ATP?
1: From Creatine Phosphate
2: Anaerobic Glycolysis
3: Aerobic respiration
What is the Process of Creatine Phosphate?
While muscle is relaxed it produces more ATP than it needs for resting metabolism.
ATP is used for the production of “Creatine Phosphate”.
When contraction begins & the ADP level rises, (CK) catalyses the transfer of high energy to phosphate from creatine back to ADP.
Where does Creatine get synthesized in the body?
In the liver, kidneys and pancreas and then transported to muscle fibers.
What is the process of Anaerobic Glycolysis?
When Creatine in the muscle is gone, Glucose is catabolized to generate ATP.
What is the process of Aerobic Respiration?
If enough O2 is present then the Pyruvic Acid formed by the Glycolysis enters the mitochondria, where it undergoes “Aerobic Respiration”.
What type of ATP generation does not require O2?
Anaerobic Glycolysis.
What is Muscle Fatigue?
The inability of a muscle to maintain force of contraction after prolonged activity is called Muscle Fatigue.
What is O2 debt?
…
What is the extra O2 used for in the body after Exercise has stopped?
There are 3 things it can be used for:
What is Creatine Phosphate?
This is an Energy rich molecule that is found in muscle fibres.
What is the Enzyme used for turning ATP into creatine phosphate & ADP?
Creatine Kinase (CK).
What is the Molecule Creatine?
It is a small amino acid like molecule that is Synthesized in the liver, kidneys and pancreas then transported to a muscle fiber.
Where can Creatine phosphate be found in the muscle fiber?
It is plentiful in the Sarcoplasm of the muscle cell / Fiber of a Relaxed muscle.
What is the Molecule that is 3-6 times more powerful than ATP?
Creatine Phosphate.
What is the end result of Creatine phosphate?
The canalization of creatine to ADP generates new ATP molecules.
What is the first type of ATP formation from the muscle cells?
It is creatine phosphate because it takes very little time.
When does Anaerobic Glycolysis begin In the muscle?
It starts when the muscle activity continues and the supply of creatine phosphate within the muscle fiber is depleted.
What is the process called “Facilitated Diffusion”?
This process is when Glucose passes into the muscle fiber from the blood.
What happens during Anaerobic Glycolysis?
When the Glucose is quickly broken down into 2 molecules of Pyruvic Acid by the Muscles Glycogen.
Then Lactic Acid is formed as a byproduct.
What are the steps to Aerobic respiration?
Amino acids form protein breakdown
Fatty acids liberated from adipose tissue
Pyurvic Acid from glycolysis
O2 from Hemeglobin in the blood or myoglobin from the Muscle tissue
All used for the production of ATP in the Mitochondria
Kerbs Cycle.