Principles 1 Flashcards

1
Q

How do you get a xenobiotic to the brain?

A

absorption
distribution
metabolism
elimination

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2
Q

what are some advantages and disadvantages of oral pharmokinetics

A

potential large duration of action
compliance is easier
potential liver damage

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3
Q

what are some advantages and disadvantages of intervenus pharmokinetics

A

immediate bioavailability
some risks
no first past effect
better to control plasma concentration

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4
Q

what are some advantages and disadvantages of transdermal pharmokinetics

A

slow steady absorption
control location of action
can be manipulated by the temperature

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