Acetylcholine Neurotransmission

Question 1

what is the heart drug affecting the mAChR

Answer 1

Atropine -> Atropine sulfate injection
- non-selective mAChR antagonist
- indicated for: (1) prevention and treatment of bradycardia
caused by excessive vagal stimulation
(2) during cardiopulminary resuscitation to
treat excessive vagal tone
and…
(3) antidote to organophosphate poisoning
(4) antidote to poisoning from muscarinic
mushrooms (e.g. amanita)

Question 1

what is the GI drug affecting the mAChR

Answer 1

Dicyclomine -> dicyclomine hydrochloride capsules
- non-selective mAChR antagonist
- indicated for: the treatment of functional gastrointestinal tract
conditions involving smooth muscle spasm such
as irritable colon (mucous colitis, spastic colon,
irritable bowel syndrome) and spastic constipation