primary amenorrhea Flashcards
primary amenorrhea
girl never bled
when is the upper limit of normal secondary sex characteristics arrive in girls
13
when is the upper limit of menarche
15
craniopharyngioma
anterior pituitary syndrome. no FSH/LH.
Kallman’s syndrome
deficiency in hypothalamus. lose pulsatile GnRH and thus FSH/LH
why do Kallman’s and craniopharyngioma look the same
because they affect the same axis and and produce the same symptoms. no development of the secondary sex characteristics and no menarche. NO FSH/LH!
where does craniopharyngioma affect?
anterior pituitary
where does Kallman’s affect?
hypothalamus
treatment for Kallman’s/craniopharyngioma
give estrogen and progesterone and resect any tumors. she develops niormal
what is primary amenorrhea and anosmnia
Kallman’s every time.
Turner’s syndrome affect?
the ovaries
what does Turner’s do
No estrogen/progesterone is made and thus it disinhibits FSH/LH so they will be elevated.
mullerian agenesis
genetically female but amenorrhea because no uterus. idiopathic loss of mullerian ducts.. Will have secondary sex characteristics with female genitals. karytype x,x. normal levels of testosterone, FSH/LH. may need to elevate the vagina surgically.
androgen insensitivity syndrome
genetically male with a resistance to testosterone. female sex characteristics. external female genitalia. no uterus, tubes. elevated testosterone with peripheral conversion to E/P. ultrasound will show testes. still need to elevate the vagina for improvement of sexual satisfaction. karyotype genetically male.
what is really important for androgen insensitivity syndrome
must remove the testes when age 21 because they are undescended and can cause testicular cancer.
NEED orchiectomy.
