Moles Flashcards

1
Q

what are moles?

A

gestational trophoblastic disease.

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2
Q

which moles are malignant

A

invasive molar disease and choriocarcinoma

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3
Q

complete mole

A

NO fetal parts. Completely chromosomal and all spermal. normal fertilization process but with a broken egg, thus the egg DNA breaks down and the sperms double.

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4
Q

How do complete moles groqw

A

very fast.

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5
Q

what helps diagnose complete Mole

A

size-date discrepency, high b-hCG, hyperemesis gravidarum, hyperthyroid. grape-like mass protruding through cervix.

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6
Q

what tests and results for complete mole?

A

transvaginal ultrasound –snow storm pattern.

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7
Q

How to treat complete mole

A

suction curretage. and follow the HCG for a year while on oral contraception. If treatment effective HCG will go down to zero.

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8
Q

What is incomplete mole

A

arise from disperm fertilization. this causes abnormal genetic complement. It contains fetal parts, incmpletely chromosomal has 69 chromosomes, has egg parts.

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9
Q

what causes incomplete mole

A

good egg, bad fertilization (two sperm).

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10
Q

treatment for incomplete mole

A

same as complete.

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11
Q

choriocarcinoma?

A

malignant and caused by gestational contents. gestational trophoblastic neoplasm.

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12
Q

how does the patient present with chorio?

A

elevated b-HCG, similar to molar pregnancies.

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13
Q

when can chorio occur?

A

after miscarriage, molar pregnancies and normal pregnancies

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14
Q

what cause of chorio has the worst prognosis

A

after normal pregnancy, because thats not supposed to happen.

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15
Q

how to test for chorio

A

transvaginal ultrasound with biopsy or curettage.

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16
Q

where does chorio like to mets? (2)

A

lungs and the brain

17
Q

treatment for chorio

A

both surgical and chemo
total hysterectomy (stage I) and debulking (stage III)
Chemo (MAC) methotrexate, actinomycinD cyclophosphamide