Prescription Drugs: Lichtblau Flashcards
What are the 3 drug classes of concern for prescription drug abuse?
Opioids, Anxiolytics, CNS Stimulants
What is abuse potential of opioids based on?
The ability of the drug to produce a state in which the user is indifferent to his/her environment.
What is abuse potential of Anxiolytics based on (bentos, barbs, etc…)?
Their ability to induce “disinhibition euphoria”. *Exactly the same effect you get if you titrate yourself properly on alcohol. “white collar alcoholism”
What is the abuse potential of CNS stimulants?
Their ability to increase wakefulness, attentiveness, and increase athletic performance.
What does the WHO consider the most dangerous drug in the world?
Alcohol because it is easy access and it causes cellular damage
What is a psychoactive drug?
any drug that affects behavior
Is every psychoactive drug abused? Ex. anti-depressants
no: they are psychoactive but they are not abused
Who determines what drug abuse is?
society, not medicine
Tolerance?
if you give a drug repeatedly, you get smaller and smaller effect or to get the same effect you need to keep escalating the doses
Cross tolerance
to drugs in the same category (opioids, bezos, barbs…within each individual group)
Tolerance to opioids, what develops rapidly and what develops slowly?
To the analgesic effects: rapid, the constipating effects: slow
Psychological dependence
you think you need the drug to have a sense of well-being
Physical dependence
some sort of change at the cellular level, if you quit giving drug person will go through withdrawal.
Note: Withdrawal from Benzodiazepines is life threatening! It can trigger seizures and arrhythmias!
Withdrawal from opioids is not life threatening
Psychological dependence with which classes?
all 3
physical dependence with which classes?
Opioids, Benzodiazepines, (stimulants are questionable)