PRELIM LEC: Fundamental Concepts in Analytical Procedures (BISHOP) Flashcards

ref: Advance Class Discussion and Chapter 1 of Bishop

1
Q

to perform analytic procedures that yield accurate and precise information, aiding in patient
diagnosis and treatment

A

CLINICAL CHEMISTRY

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2
Q

defines the physical quantity or dimension, such as mass, length, time, or volume.

A

UNIT

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3
Q

This system was devised to provide the global scientific community with a uniform method
of describing physical quantities

A

SI (SYSTEM INTERNATIONAL UNIT) UNIT

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4
Q

subclassifications OF SI UNITS:

A

basic unit
derived unit

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5
Q

is a derivative or a mathematical function describing one of the basic units

A

derived units

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6
Q

This group develops standards of practice, definitions, and guidelines that can be adopted by everyone in a given field, providing for more uniform terminology and less confusion.

A

International Organization for Standardization, often referred to as ISO

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7
Q

require manufacturers to indicate any physical or biologic health hazards and precautions needed for
the safe use, storage, and disposal of any chemical

A

Occupational Safety and Health Administration (OSHA)

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8
Q

is required to provide technical data sheets for each chemical manufactured on a document called a Safety Data Sheet (SDS)

A

manufacturer

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9
Q

certified standard reference materials (SRMs) are used instead of ACS primary standard materials.

A

Institute of Standards and Technology (NIST)

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10
Q

established specifications for AR grade chemicals, and chemical manufacturers will either meet or exceed these requirements

A

American Chemical Society (ACS)

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11
Q

has been purified to remove almost all organic materials, using a technique of distillation much like that found in organic chemistry laboratory distillation experiments in which water is boiled and vaporized

A

Distilled water

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12
Q

are excellent in removing particulate matter, microorganisms, and any pyrogens or endotoxins

A

Ultrafiltration and nanofiltration, like distillation

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13
Q

is purified from previously treated water, such as prefiltered or distilled water

A

Deionized water

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13
Q

has some or all ions removed, although organic material may still be present, so it is neither pure nor sterile

A

Deionized water

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14
Q

is produced using either an anion or a cation exchange resin, followed by replacement of the removed ions with hydroxyl or hydrogen ions

A

Deionized water

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15
Q

is a process that uses pressure to force water through a semipermeable membrane, producing water that reflects a filtered product of the
original water. It does not remove dissolved gases.

A

Reverse osmosis

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16
Q

uses an anion resin followed by a cation resin. The
different resins may be in separate columns or in the same column. This processis excellent in removing dissolved ionized solids and dissolved gases.

A

two-bed system

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17
Q

may be used for the pretreatment of water

A

Reverse osmosis

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18
Q

which removes some trace organic material or
sterilization processes at specific wavelengths, when used in combination with ozone treatment, can destroy bacteria but may leave behind residual products.

A

Ultraviolet oxidation

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19
Q

These techniques are often used after other purification processes have been completed.

A

Ultraviolet oxidation

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20
Q

are those properties related to the number of solute
particles per solvent molecules, not on the type of particles present

A

Colligative Properties

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21
Q

Colligative Properties

A

osmotic pressure, vapor pressure, freezing point, and boiling point

22
Q

is the pressure exerted by the vapor when the liquid solvent is in equilibrium with the vapor.

A

Vapor pressure

23
Q

is the temperature at which the first crystal (solid) of solvent forms in equilibrium with
the solution

A

Freezing point

24
is the pressure that opposes osmosis when a solvent flows through a semipermeable membrane to establish equilibrium between compartments of differing concentration.
Osmotic pressure
24
is the temperature at which the vapor pressure of the solvent reaches atmospheric pressure (usually one atmosphere)
Boiling point
25
The osmotic pressure of a dilute solution is **directly proportional** to the concentration of the molecules in solution
t
26
27
is a measure of the ability of a solution to accept or donate electrons
Redox potential, or oxidation–reduction potential
28
Substances that donate electrons
reducing agents
29
those that accept electrons are considered
oxidizing agents
30
is a measure of how well electricity passes through a solution
Conductivity
31
are weak acids or bases and their related salts that, as a result of their dissociation characteristics, minimize changes in the hydrogen ion concentration.
Buffers
32
are designed to hold different volumes rather than one exact amount
Erlenmeyer flasks and Griffin beakers
32
represents the negative or inverse log of the hydrogen ion concentration
ph
33
re long, cylindrical tubes usually held upright by an octagonal or circular base.
Graduated cylinders
34
The compound and the associated water are called a
hydrate
35
When the water of crystallization is removed from the compound
anhydrous
36
Substances that take up water on exposure to atmospheric conditions
hygroscopic
37
These materials make excellent drying substances
desiccants
38
If these compounds absorb enough water from the atmosphere to cause dissolution
deliquescent substances
39
samples measure blood gases (partial pressures of oxygen and carbon dioxide) and pH
Arterial blood
40
what are the primary arterial sites
radial, brachial, and femoral arteries
41
mechanical destruction of red cells that can result in hemoglobin release
hemolysis
42
does not contain fibrinogen (i.e., there is less protein in serum than plasma) and some potassium is released from platelets (serum potassium is slightly higher in serum than in plasma)s
plasma
43
does not contain an anticoagulant, the blood's clotting factors are active in forming a clot incorporating the cells
serum
43
Prolonged tourniquet application causes a stasis of blood flow and an increase
hemoconcentration
44
Having patients open and close their fist during phlebotomy is of no value and may cause an increase in
potassium
45
is an ultrafiltrate of the plasma and will, ordinarily, reflect the values seen in the plasma
CSF
46
increased bilirubin pigment
icterus
47
Samples should be analyzed within
4 hours
48
the presence of turbidity often associated with _________ (increased lipids)
lipemia
49
to minimize the effects of evaporation, samples should be
properly capped and kept away from areas of rapid airflow, light, and heat