PRELIM LEC: Fundamental Concepts in Analytical Procedures (BISHOP) Flashcards

ref: Advance Class Discussion and Chapter 1 of Bishop

1
Q

to perform analytic procedures that yield accurate and precise information, aiding in patient
diagnosis and treatment

A

CLINICAL CHEMISTRY

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2
Q

defines the physical quantity or dimension, such as mass, length, time, or volume.

A

UNIT

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3
Q

This system was devised to provide the global scientific community with a uniform method
of describing physical quantities

A

SI (SYSTEM INTERNATIONAL UNIT) UNIT

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4
Q

subclassifications OF SI UNITS:

A

basic unit
derived unit

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5
Q

is a derivative or a mathematical function describing one of the basic units

A

derived units

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6
Q

This group develops standards of practice, definitions, and guidelines that can be adopted by everyone in a given field, providing for more uniform terminology and less confusion.

A

International Organization for Standardization, often referred to as ISO

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7
Q

require manufacturers to indicate any physical or biologic health hazards and precautions needed for
the safe use, storage, and disposal of any chemical

A

Occupational Safety and Health Administration (OSHA)

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8
Q

is required to provide technical data sheets for each chemical manufactured on a document called a Safety Data Sheet (SDS)

A

manufacturer

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9
Q

certified standard reference materials (SRMs) are used instead of ACS primary standard materials.

A

Institute of Standards and Technology (NIST)

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10
Q

established specifications for AR grade chemicals, and chemical manufacturers will either meet or exceed these requirements

A

American Chemical Society (ACS)

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11
Q

has been purified to remove almost all organic materials, using a technique of distillation much like that found in organic chemistry laboratory distillation experiments in which water is boiled and vaporized

A

Distilled water

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12
Q

are excellent in removing particulate matter, microorganisms, and any pyrogens or endotoxins

A

Ultrafiltration and nanofiltration, like distillation

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13
Q

is purified from previously treated water, such as prefiltered or distilled water

A

Deionized water

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13
Q

has some or all ions removed, although organic material may still be present, so it is neither pure nor sterile

A

Deionized water

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14
Q

is produced using either an anion or a cation exchange resin, followed by replacement of the removed ions with hydroxyl or hydrogen ions

A

Deionized water

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15
Q

is a process that uses pressure to force water through a semipermeable membrane, producing water that reflects a filtered product of the
original water. It does not remove dissolved gases.

A

Reverse osmosis

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16
Q

uses an anion resin followed by a cation resin. The
different resins may be in separate columns or in the same column. This processis excellent in removing dissolved ionized solids and dissolved gases.

A

two-bed system

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17
Q

may be used for the pretreatment of water

A

Reverse osmosis

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18
Q

which removes some trace organic material or
sterilization processes at specific wavelengths, when used in combination with ozone treatment, can destroy bacteria but may leave behind residual products.

A

Ultraviolet oxidation

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19
Q

These techniques are often used after other purification processes have been completed.

A

Ultraviolet oxidation

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20
Q

are those properties related to the number of solute
particles per solvent molecules, not on the type of particles present

A

Colligative Properties

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21
Q

Colligative Properties

A

osmotic pressure, vapor pressure, freezing point, and boiling point

22
Q

is the pressure exerted by the vapor when the liquid solvent is in equilibrium with the vapor.

A

Vapor pressure

23
Q

is the temperature at which the first crystal (solid) of solvent forms in equilibrium with
the solution

A

Freezing point

24
Q

is the pressure that opposes osmosis when a solvent flows through a semipermeable membrane to establish equilibrium between compartments of differing concentration.

A

Osmotic pressure

24
Q

is the temperature at which the vapor pressure of the
solvent reaches atmospheric pressure (usually one atmosphere)

A

Boiling point

25
Q

The osmotic pressure of a dilute solution is directly proportional to the concentration of the molecules in solution

A

t

26
Q
A
27
Q

is a measure of the ability of
a solution to accept or donate electrons

A

Redox potential, or oxidation–reduction potential

28
Q

Substances that donate electrons

A

reducing agents

29
Q

those that accept electrons are considered

A

oxidizing agents

30
Q

is a measure of how well electricity passes through a solution

A

Conductivity

31
Q

are weak acids or bases and their related salts that, as a result of their dissociation characteristics, minimize changes in the hydrogen ion concentration.

A

Buffers

32
Q

are designed to hold different
volumes rather than one exact amount

A

Erlenmeyer flasks and Griffin beakers

32
Q

represents the negative or inverse log of the hydrogen ion concentration

A

ph

33
Q

re long, cylindrical tubes usually held upright by an
octagonal or circular base.

A

Graduated cylinders

34
Q

The compound and the associated water are called a

A

hydrate

35
Q

When the water of crystallization is removed from the compound

A

anhydrous

36
Q

Substances that take up water on exposure to atmospheric
conditions

A

hygroscopic

37
Q

These materials make excellent drying substances

A

desiccants

38
Q

If these compounds absorb enough water from the atmosphere to cause dissolution

A

deliquescent substances

39
Q

samples measure blood gases (partial pressures of oxygen and carbon dioxide) and pH

A

Arterial blood

40
Q

what are the primary arterial sites

A

radial, brachial, and femoral arteries

41
Q

mechanical destruction of red cells
that can result in hemoglobin release

A

hemolysis

42
Q

does not contain fibrinogen (i.e., there is less protein in serum than plasma) and some potassium is released from platelets (serum potassium is slightly higher in serum than in plasma)s

A

plasma

43
Q

does not contain an anticoagulant, the blood’s clotting factors are active in forming a clot incorporating the cells

A

serum

43
Q

Prolonged tourniquet application causes a
stasis of blood flow and an increase

A

hemoconcentration

44
Q

Having patients open and close their fist during phlebotomy is of no value and may cause an increase in

A

potassium

45
Q

is an ultrafiltrate of the plasma and will, ordinarily, reflect the values seen in the plasma

A

CSF

46
Q

increased bilirubin pigment

A

icterus

47
Q

Samples should be analyzed within

A

4 hours

48
Q

the presence of turbidity often associated with _________ (increased lipids)

A

lipemia

49
Q

to minimize the effects of evaporation, samples should be

A

properly capped and kept away from
areas of rapid airflow, light, and heat