MIDTERM LEC: LIPIDS AND LIPOPROTEINS Flashcards
are basically fats
Lipids
Biological function of lipids:
- Fuel
- Insulation
- Protect or cushion internal organs
- Building blocks of other substances in the body
- Constituent of cell walls
comprises 95% of lipids in food and human body
Triglycerides
major class of dietary lipids
Triglycerides
lipids that are solid at RT
FATS
lipids that are liquid at RT
OILS
Phospholipids FORMS:
- 70% Lecithin/Phosphatidylcholine
- 20% Sphingomyelin
- 10% Cephalin
not used for energy
Cholesterol
- precursor of steroid hormones
Cholesterol
constituent of cell membranes
Phospholipids
building blocks of lipids
Fatty Acids
Lipoproteins
Lipoproteins
5 TYPES Lipoproteins
- Chylomicrons
- Very Low Density Lipoprotein
- Intermediate Density Lipoprotein
- Low Density Lipoprotein
- High Density Lipoprotein
Most dense to the least (based on density):
HDL > LDL > VLDL > Chylomicron
function: transport TAG absorbed from the intestine to adipose, cardiac & skeletal muscle
Chylomicron
Heaviest to lightest (based on Molecular Weight):
Chylomicron > VLDL > LDL > HDL
Chylomicron
- Contains:
85-92% TAG
6-12% phospholipids
1-3% cholesterol
1-2% proteins
Responsible for post-prandial turbidity of sample
Chylomicron
- Lipoprotein made in the liver
Very Low Density Lipoprotein (VLDL)
Second hightest TAG content
Very Low Density Lipoprotein (VLDL)
function: Endogenous transport of TAG; body’s internal transport mechanism for lipids
Very Low Density Lipoprotein (VLDL)
VLDL remnant
Intermediate Density Lipoprotein (IDL)
similar to LDL wherein it transports TAG, fats and cholesterol and can also promote the growth of atheroma
Intermediate Density Lipoprotein (IDL)
Responsible for fasting hyperlipidemic turbidity of
sample
Very Low Density Lipoprotein (VLDL)
function: enables fats and cholesterol to move within water-based solution of the bloodstream
Intermediate Density Lipoprotein (IDL)
products of VLDL and IDL metabolism
Low Density Lipoprotein (LDL)
most cholesterol-rich
Low Density Lipoprotein (LDL)
function: principal cholesterol and fat transport in blood
Low Density Lipoprotein (LDL)