Preimplantation genetic testing (PGT-A)

Question 1

age at which PGT-A improves clinical pregnancy rates

Answer 1

37

Question 2

number needed to treat with PGT-A to have one additional live birth

Answer 2

21

Question 3

consider PGT-A for paternal age over

Answer 3

50 (increased risk of aneuploidy)

Question 4

most beneficial clinical utility of PGT-A

Answer 4

increase utilization of eSET

Question 5

time to successful pregnancy for RPL was shorter for

Answer 5

expectant management (3 vs 6 months)

Question 6

more likely to result in live birth (day 5/day6 embryo)

Answer 6

same

Question 7

men with oligozoospermia have a increased risk in __________aneuploidies

Answer 7

sex chromosome

Question 8

in oligozoospermic men undergoing ICSI there is increased aneuploidy in chromosomes

Answer 8

1, 2, 11, 18

Question 9

define mosaicism

Answer 9

two more cell populations with different chromosomal complements being present in the same embryo

Question 10

benefits for SNP microsarray

Answer 10

determine source from egg or sperm, detect triploidy and tetraploidy, detecting low levels of mosaicism