Obesity Flashcards

1
Q

MOA of obesity for oligospermia

A

peripheral aromatization of androgens leading to negative feedback by estrogen on HPT axis

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2
Q

FDA approved treatment for weight loss

A

phentermine + topiramate

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3
Q

MOA of metformin

A

biguanide that increases peripheral sensitivity to insulin and decrease hepatic glucose production (minimal weight loss)

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4
Q

MOA of phentermine/topiramate for weight loss

A

GABA receptor modulator, norepinephrine releasing agent

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5
Q

side effects of phentermine

A

headache, high blood pressure, tachycardia, insomnia, dry mouth, constipation

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6
Q

weight loss improves LBR after treatment (T/F)

A

false

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7
Q

weight loss improves unassisted conception in anovulatory women (T/F)

A

true

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