Postoperative Adhesions Flashcards
vasoactive substances released in response to peritoneal trauma
histamines, cytokines, growth factors
vasoactive substances cause
increased vascular permeability and fibrin exudates
normal fibrinolytic activity leads to breakdown of fibrinous exudate within
72 hours
decreased fibrinolytic activity leads to
fibrin deposition and capillary ingrowth leading to adhesion formation
adhesions affect fertility adversely by
distorting adnexal anatomy and interfering with gamete and embryo transport
surgical techniques that reduce adhesions
gentle tissue handling, hemostasis, excision of necrotic tissue, minimization of necrosis, nonreactive suture materials
anterior wall adhesions risk is related to ______ of the abdominal incision
length (thus laparoscopy < laparotomy)
anti-inflammatory agents (do/do not) reduce postoperative adhesions
do not
peritoneal instillation (icodextrin, heparin) (do/do not) reduce postoperative adhesions
do not
seprafilm is composed of
HA/CMC (hyaluronic acid and carboxuymethyl cellulose)
interceed is composed of
oxidized regenerated cellulose
interceed is rendered infective when saturated with
blood