Preeclampsia Flashcards

1
Q

What is preeclampsia?

A

New hypertension in pregnancy (>140/90) and proteinuria >20/40

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2
Q

What does preeclampsia affect?

A

Several organs including kidneys, brain, liver, NS

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3
Q

What are the signs and symptoms of preeclampsia?

A
  • New hypertension
  • Proteinuria
  • Headache +/- visual disturbances
  • Epigastric pain
  • Sudden oedema in hands/feet/face
  • Reduced urine output
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4
Q

What are the 3 main complications of preeclampsia?

A
  • Eclampsia
  • HELLP syndrome
  • Disseminated intravascular coagulation
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5
Q

What is DIC?

A

Blood clots throughout the body

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6
Q

What is HELLP syndrome?

A
  • Haemolysis
  • Elevated liver enzymes
  • Low platelets
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7
Q

What are some possible foetal complications of preeclampsia?

A
  • IUGR
  • Oligohydramnios
  • Hypoxia
  • Placental abruption
  • Premature delivery
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8
Q

What medication is given to women with preeclampsia?

A

Asthmatic +/or Afro-Caribbean = Nifedipine (+ Hydralazine infusion)
Otherwise = Labetalol

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9
Q

What is eclampsia?

A

Seizures associated with preeclampsia (medical emergency)

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10
Q

What drug is used to treat eclamptic seizures?

A

Magnesium sulphate

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11
Q

What is the initial management for women having an eclamptic fit?

A
  • Call for help
  • L lateral position (if poss)
  • High flow O2
  • IV access and bloods
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12
Q

What are the doses used for MgSO4?

A

Loading = 4g over 5 mins
Maintenance = 1g/hr for 24 hours after last fit
Recurrent seizures = 2g bolus after each, then recommence maintenance dose

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13
Q

What bloods should be taken for preeclampsia?

A

FBC, G+S, Us+Es, LFTs, clotting, Mg levels if needed

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14
Q

What else should be monitored?

A
  • Observations (MEWS)
  • Catheterise and fluids
  • CTG
  • Neuro observations
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15
Q

What should NOT be given in 3rd stage?

A

Ergometrine

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16
Q

What is the initial dose of Nifedipine?

A

10mg

17
Q

What is the initial dose of Labetalol?

A

200mg

18
Q

What is important to consider in preeclamptic women during labour?

A

Keep an eye on risk of fluid overload - strict fluid balance (80ml/hr)

19
Q

What causes eclamptic fits?

A

Cerebral oedema

20
Q

What causes HELLP syndrome?

A
  • Activation of coagulation system = increased fibrin deposits
  • Fibrin deposits on blood vessels walls = blood clots and low platelet count
  • Destruction of liver cells
21
Q

What causes epigastric pain?

A

Vasoconstriction, causing a reduced blood supply to the liver