potassium-sparing Flashcards
1
Q
MOA
A
-inhibits the reabsorption of sodium in exchange for potassium and hydrogen ions by exerting a direct effect on the distal renal tubule
2
Q
drug
A
• Amiloride
3
Q
adverse effect
A
- Photosensitivity, rash (triamterene)
* Hyperkalemia, hyperuricemia
4
Q
indication
A
edema
5
Q
monitoring
A
- Potassium level
* 7-14 days after initiation
6
Q
comment
A
- K-sparing diuretics and ACEi may enhance hyperkalemic effects
- Avoid in pts with CrCl <10 ml/min
