a-1 blocker Flashcards
1
Q
MOA
A
reduction in total peripheral resistance and directly relaxes vascular smooth muscle, which may be related to postsynaptic alpha-adrenoceptor blockade
2
Q
drug names
A
- Doxazosin
- Prazosin
- Terzosin
3
Q
adverse effect
A
- Syncope
- Dizziness
- Palpitations
- Orthostatic hypotension
4
Q
indication
A
- BPH
* PTSD
5
Q
monitoring
A
• urinary symptoms
6
Q
comment
A
• Start slowly, consider first dose at night
Contraindication:
• Hypersensitivity