loops Flashcards

1
Q

MOA

A

-Inhibits reabsorption of Na+ and Cl- in the ascending loop of Henle and distal renal tubule, interfering with the chloride-binding cotransport system increased excretion of water, Na+, Cl-, Mg, and Cl

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2
Q

drugs

A
  • Bumetanide
  • Furosemide
  • Torsemide
  • Ethacrynic acid
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3
Q

indication

A

edema

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4
Q

adverse effects

A
  • Hypokalemia
  • Hyponatremia
  • Metabolic alkalosis
  • Hyperuricemia
  • Hypomagnesemia
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5
Q

monitoring

A
  • Electrolytes (hypo-K)
  • BUN, SCr
  • I & O
  • 7-14 days after initiation
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6
Q

comment

A

• Avoid in pts with sulfonamide allergy, except ethacrynic acid

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