loops Flashcards
1
Q
MOA
A
-Inhibits reabsorption of Na+ and Cl- in the ascending loop of Henle and distal renal tubule, interfering with the chloride-binding cotransport system increased excretion of water, Na+, Cl-, Mg, and Cl
2
Q
drugs
A
- Bumetanide
- Furosemide
- Torsemide
- Ethacrynic acid
3
Q
indication
A
edema
4
Q
adverse effects
A
- Hypokalemia
- Hyponatremia
- Metabolic alkalosis
- Hyperuricemia
- Hypomagnesemia
5
Q
monitoring
A
- Electrolytes (hypo-K)
- BUN, SCr
- I & O
- 7-14 days after initiation
6
Q
comment
A
• Avoid in pts with sulfonamide allergy, except ethacrynic acid