Post-translational Modification et al

Question 1

Following translation we have only the ________ structure of the protein.

Answer 1

Primary

Question 2

The protein can then mature to…

Answer 2

Secondary, Tertiary & Quaternary Structures

Question 3

How can amino acids be modified?

Answer 3

Addition of saccharides or lipids
Cleavage of certain amino acids
Targeting Signals also added!

Question 4

Where does amino acid modification take place?

Answer 4

Mostly in Golgi Apparatus

Question 5

Control of transcription is by the presence or absence of…

Answer 5

Transcription Factors

Question 6

DNA packing & unpacking is up to the:

Answer 6

Histones

Question 7

Acetylation turns genes..

Answer 7

On! (Adding COCH3)

Question 8

Methylation turns genes..

Answer 8

Off (CH3)

Question 9

Transcription factors, simply…

Answer 9

Regulate Initiation

Question 10

Activators can be molecules that bring TF’s:

Answer 10

Closer/close to promoter

Question 11

Once the TF’s have been brought around:

Answer 11

RNA polymerase can get started!

Question 12

Activators –

Answer 12

Increase Expression

Question 13

Repressors –

Answer 13

Shut down expression

Question 14

Genes being turned on or off are the result of:

Answer 14

Site Specific Activators

Question 15

During RNA processing, removing introns & exons can lead to:

Answer 15

Alternative Splicing

Question 16

T/F Depending on what’s cut (introns) and what exons and up where, we can make different possibly thousands of proteins.

Answer 16

TRUE