Post-thrombotic Syndrome

Question 1

What are the clinical features of post-thrombotic syndrome?

Answer 1

• Painful, heavy calves
• Pruritus
• Swelling
• Varicose veins
• Venous ulceration

Question 2

What is the physiological cause of post-thrombotic syndrome?

Answer 2

Inflammation secondary to chronic venous hypertension due to venous insufficiency and venous outflow obstruction.

Question 3

How should you prevent post-thrombotic syndrome?

Answer 3

Compression stockings should be offered 1 week after diagnosis or when swelling is reduced sufficiently and as long as there are no contraindications. (Ensure ankle pressure greater than 23 mmHg.)

Question 4

What advise should you give about wearing compresion stockings?

Answer 4

• Advise patients to continue wearing the stockings for at least 2 years
• Ensure that the stockings are replaced two or three times per year or according to the manufacturer’s instructions
• Advise patients that the stockings need to be worn only on the affected leg or legs.