Hypertension Flashcards

1
Q

Before diagnosing hypertension, NICE recommend doing it in both arms. If one arm is hypertensive but the other isn’t, what do you do?

NOTE: What other pathological causes can cause a blood pressure variation between arms?

A

The lower reading of the two determines management.

I.e. use the lower arm in future.

NOTE: Aortic dissection, Aortic stenosis.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

If someone has postural hypotension what should you do as a GP?

A
  1. Review their medication
  2. Measure subsequent BPs with the person standing.
  3. Consider referral if symptoms persist.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Stage 1 Hypertension is classified as:

A

Clinic BP >= 140/90

OR

ABPM daytime average or HBPM average of >= 135/85

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Stage 2 Hypertension is classified as:

A

Clinic Bp >= 160/100 mmHg

OR

ABPM daytime average or HBPM daytime average of >= 150/95

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Severe hypertension is classified as:

A

Clinic SBP >= 180mmHg

OR

Clinic DBP of >= 110mmHg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

If someone has severe hypertension (SBP >=180 or DBP >=110) what should your work up and management strategy be?

A
  1. Immediately start treating.
  2. Fundoscopy -papilloedema or retinal haemorrhage => Specialist within 24 hours.
  3. Referral if phaeochromcytoma is suspected. Symptoms:
    • Paroxysmal hypertension
    • Postural hypotension
    • Headache
    • Palpitations
    • Pallor
    • Diaphoresis (Excessive sweating)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What lifestyle advise should be given?

A
  1. A low salt diet is recommended - aiming for less than 6g/day, ideally 3g/day.
  2. Caffeine intake should be reduced.
  3. Other bits of advise: stop smoking, drink less alcohol, eat a balanced diet rich in fruits and vegetables, exercise more and lose weight.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

When should we treat Stage 1 Hypertension?

A

Treat if <80 years old.

AND there is

  • Target organ damage
  • Established CVD
  • Renal disease
  • Diabetes
  • 10 year cardiovascular risk equivalent to 20% or greater.

NOTE: Don’t forget to offer lifestyle advise.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Someone has Stage 2 Hypertension. This needs treating. What investigations and workup should you do for the patient before deciding to treat?

A
  1. Offer ambulatory BP monitoring
  2. Look for end organ damage
    • ACR
    • Dipstick for haematuria
    • Bloods: HbA1C, U&Es, Cholesterol and HDL. Add CRP to screen for secondary causes.
    • Fundoscopy
    • ECG
  3. CV Risk tool - QRISK2
  4. Offer drug treatment regardless of age.

NOTE: If <40 years consider specialist referral to exclude secondary cause.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Describe the stepwise treatment of Hypertension

A
  1. <55 years offer ACE-i OR >55 years or Afro-carribean offer CCB.
  2. ACE-i + CCB (If afro-carribean offer A2RB)
  3. A+C+D (thiazide diruetic).
    • Clorthialidone 12.5-25mg OD or indapamide MR 1.5mg or SR 2.5mg OD.
  4. Resistant Hypertension - Consider:
    • Further diuretic. (e.g furosemide)
    • If potassium <4.5mmol/l add spironolactone 25mg OD
    • If potassium >4.5mmol/l add higher dose thiazide-like diuretic treatment.
    • If further diuretic therapy not tolerated or is contraindicated or ineffective consider alpha-blocker or beta-blocker.
  5. Refer to specialist
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the blood pressure targets by age?

A

< 80 years

  • Clinic BP of 140/90mmHg or ABPM/HBPM of 135/85mmHg

>80 years

  • Clinic BP of 150/90mmHg or ABPM/HBPM of 145/85 mmHg
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the definition of postural hypotension?

A

A fall in SBP of more than 20mmHg after 1 minute of standing.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

When measuring CVD risk, what assessment tool should we use?

Framingham or QRISK 2

A

QRISK 2 - it is more accurate for the British population.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Why have beta-blockers been removed with regards to treating hypertension?

A

They are less likely to prevent stroke and potential impairment of glucose tolerance.

(As demonstrated in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is a stronger factor for resistant hypertension? A high BMI, Alcohol or Poor diabetic control?

A

High BMI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What % of cases of resistant hypertension have a secondary cause?

A

10%

17
Q

Your next appointment is with a 47-year-old woman. She has come for the results of her ambulatory blood pressure monitoring (ABPM). This was arranged as a clinic reading one month ago was noted to be 146/92 mmHg. The results of the ABPM show an average reading of 126/78 mmHg. What is the most appropriate course of action?

A

In this situation where the ABPM has shown a sub-threshold average blood pressure NICE recommend offering to measure the patient’s blood pressure at least every 5 years.

18
Q

How should ABPM be measured?

A

2 measurements per hour during waking hours.

Use the average of 14 values (7 days)

19
Q

When should HBPM be offered?

A

If ABPM is not tolerated or declined.

20
Q

How should HBPM be monitored?

A
  • Each BP is 2 consecutive measurements.
  • Taken whilst seated
  • Recorded twice daily.
  • Ideally for 7 days (Minimum of 4 days)
  • Discard the measurements on the first day and use the average of the remaining days.
21
Q

NICE states CCBs are firstline in patients > 55 years. When would this differ?

A

If they have oedema, heart failure or the patient is at risk of heart failure.

Then NICE state they should be on thiazide diuretics like Indapamide or Chlorthalidone.