posology Flashcards

1
Q

posology

A

study of how much
study of dosage of medicine

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2
Q

medicinal effect

A

therapeutic - desirable
adverse - undesirable, negative

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3
Q

factors affecting dose determine

A

pharmacodynamics - how medicine effect body
pharmacokinetics (absorption metabolism distribution excretion)
patient factors
drug factors - drug interactions formulation route therapeutic index

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4
Q

therapeutic index

A

ratio toxic amount; ratio safe amount
10./1.5 =6.667
depends toxic effect being measured - seizures vs death

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5
Q

median effective toxic lethal dose ED50 TD50 LD50

A

dose required where 50% of test population gets desired effect/toxic effect/killed

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6
Q

dose response curves

A

look at em

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