posology Flashcards
1
Q
posology
A
study of how much
study of dosage of medicine
2
Q
medicinal effect
A
therapeutic - desirable
adverse - undesirable, negative
3
Q
factors affecting dose determine
A
pharmacodynamics - how medicine effect body
pharmacokinetics (absorption metabolism distribution excretion)
patient factors
drug factors - drug interactions formulation route therapeutic index
4
Q
therapeutic index
A
ratio toxic amount; ratio safe amount
10./1.5 =6.667
depends toxic effect being measured - seizures vs death
5
Q
median effective toxic lethal dose ED50 TD50 LD50
A
dose required where 50% of test population gets desired effect/toxic effect/killed
6
Q
dose response curves
A
look at em