Polypharmacy and deprescribing

Question 1

What is polypharmacy?

Answer 1

> 5 medications

Question 2

How does distribution of drugs change in the elderly?

Answer 2

Question 3

Do water soluble drugs have higher or lower serum levels? How would you change drug dosage in the elderly for gentamicin and digoxin?

Answer 3

Question 4

What drugs alter absorption?

Answer 4

Question 5

What physiological changes can affect drug absorption?

Answer 5

Question 6

How does reduced liver mass and blood flow affect drug metabolism?

Answer 6

Question 7

What drugs are enzyme inhibitors?

Answer 7

Question 8

What drugs are enzyme inducers?

Answer 8

Question 9

How does reduction in eGFR affect elimination of medications?

Answer 9

Question 10

What are the pharmacokinetic implications of ageing?

Answer 10

Question 11

What cardiovascular pharmacodynamic implications are there in ageing?

Answer 11

Question 12

What psychotropic pharmacodynamic implications are there in ageing?

Answer 12

Question 13

What anticoagulant pharmacodynamic implications are there in ageing?

Answer 13

Question 14

What is STOPP/START?

Answer 14

Question 15

What is Beer’s criteria?

Answer 15

Question 16

What is the anticholinergic risk scale?

Answer 16