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An Antibiotics and Antifungals Review > Polyenes (Antifungal) > Flashcards

Polyenes (Antifungal) Flashcards

1
Q

What is the MOA of polyenes?

A

binds ergosterol in membrane and forms membrane pores = fungicidal

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2
Q

What are 3 common polyene medications?

A

Amphoterecin B, Abelcet, Ambisome

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3
Q

What are the antifungals of choice for severe Zygomycetes, Cryptococcal Meningitis, and severe endemic fungal infections?

A

Polyenes

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4
Q

What are 4 common side-effects of Polyene use?

A
  1. Nephrotoxicity
  2. Seizures
  3. Hypotension
  4. Bradycardia
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An Antibiotics and Antifungals Review (16 decks)

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