Flutycosine (Antifungal) Flashcards

1
Q

What is the MOA of Flutycosine?

A

5-FC interferes with DNA and protein synthesis

  • only available PO in the US
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2
Q

What drug is Flutycosine typically paired with to treat severe fungal infections?

A

Amphoterecin B

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3
Q

What are the typical medications used to treat these fungal infections:

  1. Mild-Mod Candidemia
  2. Severe Candidemia
  3. Invasive Aspergillus
  4. Mucormycosis
A
  1. Fluconazole
  2. Echinocandin (2nd: Amphoterecin B)
  3. Voriconazole (2nd: Amphoterecin B, Echinocandin)
  4. Amphoterecin B
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