Polycythaemia Flashcards

1
Q

what are the different causes of polycythaemia?

A

relative i.e. dehydration

absolute - primary (polycythaemia vera) and secondary (COPD, chronic heart failure, OSAS)

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2
Q

how does secondary polycythaemia cause a raised haematocrit?

A

due to hyoxia which stimulates excessive erythropoeitin production

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3
Q

how does primary polycthaemia cause a raised haematocrit?

A

mutation in JAK 2

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4
Q

how does relative polycythaemia cause a raised haematocrit?

A

isolated decrease in plasma volume concentrates RBC therefore causing haematocrit to rise

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5
Q

what is haematocrit and what is the normal value in males and females?

A

% RBC within the blood
males 35-40%
females 30-35%

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6
Q

how would you treat secondary polycythaemia?

A

low flow oxygen to reduce hypoxia

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7
Q

how would you treat relative polycythaemia?

A

oral rehydration or IV fluids

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8
Q

how would you differentiate between true primary or secondary polycythaemia?

A

red cell mass studies

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