Hyposplenism / splenomegaly Flashcards

1
Q

what are causes of hyposplenism?

A
splenectomy 
coeliac disease 
sickle cell disease
SLE
sarcoidosis 
graves disease
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2
Q

what are causes of a massive splenomegaly?

A
myelofibrosis 
chronic myeloid leukaemia 
visceral leishmaniasis 
malaria
Gaucher's disease
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3
Q

what are functions of the spleen?

A
filtration of blood 
removes old/damaged RBC 
controls levels of cells 
synthesises immunoglobulins 
removes microorganisms from circulation
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4
Q

where does the spleen lie?

A

between 7th - 10th ribs

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5
Q

what histological features are found in hyposplenism?

A

Howell-Jolly bodies

siderocytes

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