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Pharm I > PNS > Flashcards

PNS Flashcards

1
Q

What are the 2 major divisions of the Peripheral NS?

A

Somatic motor system

Autonomic motor system

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2
Q

Which system involves motor movement?

A

Somatic

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3
Q

Which system is self-ruling, meaning we don’t have to think about it for it to still work?

A

Autonomic motor

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4
Q

What are the 2 parts to the autonomic motor system?

A

Parasympathetic

Sympathetic

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5
Q

Which part of the autonomic motor system is the rest and digest/peace?

A

Parasympathetic

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6
Q

What are the 7 characteristics of the parasympathetic nervous system?

A 
Decreased HR
Increased Gastric secreation
Emptying bladder
Emptying bowel
Near vision
Pupil constriction
Bronchoconstriction
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7
Q

What is the sympathetic system known for?

A

Fight or flight and stress responses

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8
Q

What are the 5 characteristics of the flight or fight response?

A
  • Increased HR and BP
  • Shunting blood to skeletal muscles
  • Bronchodilation
  • Pupil dilation
  • Increased glucose (brain) and fatty acids (muscles)
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9
Q

What are the 3 cholinergic receptors of the PNS?

A

Nicotinic(n)
Nicotinic(m)
Muscarinic

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10
Q

If a given drug activates nicotinic(n), what 2 things happen in patient response?

A

Stimulation of sympathetic and parasympathetic postganglionic nerves

Release of adrenalin from adrenal medulla

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11
Q

If a given drug activates nicotinic(m), what will happen in patient response?

A

Contraction of skeletal muscle

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12
Q

If a given drug activates muscarinic, what will the patient response be in the EYES?

A

Contraction of the ciliary muscle/focuses lens on near vision

Contraction of iris sphincter muscle/causes mitosis (decreased pupil diameter)

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13
Q

If a given drug activates muscarinic, what will the patient response be in the HEART?

A

Decreased rate

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14
Q

If a given drug activates muscarinic, what will the patient response be in the LUNGS?

A

Constriction of bronchi

Promotion of secretions

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15
Q

If a given drug activates muscarinic, what will the patient response be in the BLADDER?

A
  • Contraction of detrusor (increased bladder pressure)
  • Relaxation of trigone spinchter (allow urine to leave the bladder)
  • Coordination contraction of detrusor and relaxation of trigon sphincter causing voiding of the bladder
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16
Q

If a given drug activates muscarinic, what will the patient response be in the GI?

A
  • Salivation
  • Increased gastric secretions
  • Increased intestinal tone and motility
17
Q

If a given drug activates muscarinic, what will the patient response be in the SWEAT GLAND?

A

Generalized sweating

18
Q

If a given drug activates muscarinic, what will the patient response be in the SEX ORGANS?

19
Q

If a given drug activates muscarinic, what will the patient response be in the BLOOD VESSELS?

A

VASODILATION

20
Q

What are the 5 adrenergic receptors?

A

Alpha1, alpha2, beta1, beta2, dopamine

21
Q

If a given drug activates alpha1, what will the patient response be in the EYE?

A

Contraction of the radial muscle of the iris causing mydriasis (increase in pupil size)

22
Q

If a given drug activates alpha1, what will the patient response be in the ARTERIOLES OF SKIN, VISCERA, MUCOUS MEMBRANES?

A

Constriction

23
Q

If a given drug activates alpha1, what will the patient response be in the VEINS?

A

Constriction

24
Q

If a given drug activates alpha1, what will the patient response be in the SEX ORGANS (male)?

A

Ejaculation

25
Q

If a given drug activates alpha1, what will the patient response be in the PROSTATIC CAPSULE?

A

Contraction

26
Q

If a given drug activates alpha1, what will the patient response be in the BLADDER?

A

Contraction of trigone sphincter

27
Q

If a given drug activates alpha2, what will the patient response be in the PRESYNAPTIC NERVE TERMINALS?

A

Inhibition of transmitter release

28
Q

If a given drug activates beta1, what will the patient response be in the HEART?

A
  • Increased rate
  • Increased force of contraction
  • Increase AV conduction velocity
29
Q

If a given drug activates beta1, what will the patient response be in the KIDNEY?

A

Release of renin

30
Q

If a given drug activates beta2, what will the patient response be in the ARTERIOLES OF THE HEART, LUNG, and SKELETAL MUSCLE?

31
Q

If a given drug activates beta2, what will the patient response be in the BRONCHI?

32
Q

If a given drug activates beta2, what will the patient response be in the UTERUS?

A

Relaxation

33
Q

If a given drug activates beta2, what will the patient response be in the LIVER?

A

Gycogenolysis

34
Q

If a given drug activates beta2, what will the patient response be in the SKELETAL MUSCLE?

A

Enhanced contraction

Glycogenolysis

35
Q

If a given drug activated dopamine, what will patient response be?

A

Dilation of kidney vasculature

36
Q

What receptors does epinephrine activate?

A

Alpha1
Alpha2
Beta1
Beta2

37
Q

What receptors does norepinephrine activate?

A

Alpha1
Alpha2
Beta1

38
Q

What receptors does dopamine activate?

A

Alpha1
Beta1
Dopamine

39
Q 
Sympathetic receptors memory aid:
Beta1 receptor: \_\_\_\_
Beta2 receptor: \_\_\_\_
Alpha1 receptor: \_\_\_\_
Alpha2 receptor: \_\_\_\_
A

Beta1 receptor: Heart (we only have one heart)
Beta2 receptor: Lungs (we have 2 lungs)
Alpha1 receptor: Arteries (vasoconstriction)
Alpha2 receptor: not of concern at this point

Pharm I (30 decks)

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