pneumonia Flashcards

1
Q

what is pneumonia?

A

inflammation of alveoli or interstitium of lung cause my microorganism (bacteria, viral, fungal)

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2
Q

how is pneumonia classified and what are the 4 types we went over?

A
by source of infection
major groups: - CAP: community acquired 
-HAP: hospital acquired 
minor groups: -HIV associated (immunocompromised) 
-Flu associated MRSA pneumonia
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3
Q

how long must you have been at the hospital for it to be classified as HAP?

A

48 hrs after admission

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4
Q

3 risk factors for CAP

A

extremes of age, alcoholism, other medical conditions (i.e. DM)

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5
Q

3 types of CAP

A

bacterial (worse symptoms, 85% of cases) viral (milder symptoms) fungal (only in immunocompromised people)

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6
Q

3 typical bacterial organisms that cause CAP

A

Strep Pneumo, H flu, M catarrhalis

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7
Q

which bacterial organisms for CAP are penicillin sensitive and penicillin resistant

A

Strep pneumo- sensitive
H flu- somewhat resistant- txt w/ Beta Lactamase inhib
M cattarrhalis- resistant

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8
Q

3 atypical bacterial organisms that cause CAP

A

legionella, mycoplasma, C pnemoniae

-usually less acute symptoms w/ less productive cough

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9
Q

rare bacterial pathogens that cause CAP and what are they assosciated with?

A

klebsiella (w/ alcoholism)
staph aureus (w/ flu)
* recent reports of recent fatal CA-MRSA pneumonia

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10
Q

inoculation of pneumonia

A

microaspiration

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11
Q

clinical presentation of pneumoniae, how are these different if its viral?

A

symptoms come on rapidly, early onset cough (if productive it is purulent), pleurisy (localized chest pain w/ breathing), maybe SOB and dec. pulse ox
*viral: same symptoms but more mild

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12
Q

respiratory rate w/ pneumonia

A

commonly increased

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13
Q

PE for pneumonae

A
  • bronchial breath sounds in periphery (consolidation, fluid filled causes transmitted sounds to travel)
  • dull to percussion (effusion)
  • crackles (pus in alveoli)
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14
Q

Dx for simple pneumonia (no hospital admission)

A

chest x ray (gold standard) : shows interstitial infiltrates (pus in lung tissue) or consolidation (pus in airways- alveoli)

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15
Q

txt for pneumoniae: abx?

A

tripack > Zpack

azithromycin: 1 pill/day for 3 days

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16
Q

if Dx with CAP and considering hospitalization, what two further tests will you run?

A

deep cough sputum culture before giving abx and gram stain

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17
Q

additional tests for CAP and hospitalizing… to evaluate severity..

A
pulse ox (if not as sick), ABG (if very sick) 
procalcitonin to evaluate severity (elevated w/ sepsis)
18
Q

6 signs that pt should be admitted with CAP

A

neutropenia, multilobar infection, 50+yo and other med. problems, altered mental status, low BP

19
Q

if CAP and hospitalized, what drugs (in general) are you giving?

A

IV Abx, multi-drug therapy

20
Q

4 requirements to give oral abx and discharge

A

able to take PO, WBC decreasing, afebrile, improving cough and SOB

21
Q

when txt considered failed?

A

if not better in 72 hours: this might mean you gave the wrong drug, the bug was resistant or there are other complications (i.e. empyema)

22
Q

what is empyema?

A

collection of pus in pleural cavity (abx cant reach these) (might need thoracentesis and drainage)

23
Q

symptoms get better before _____ gets better

A

chest xray (for longterm followup)

24
Q

klebsiella pneumoniae has what as a risk factor?

A

alcoholism

25
"walking pneumonae" usually refers to what?
viral pneumonia (same symptoms but more mild)
26
mortality for HAP
high: 20-50%
27
HAP is usually from what source?
bacterial
28
clinical presentation for HAP
change in clinical status: those in hospital should be improving NOT declining
29
labs and Dx test for HAP
chest Xray procalcitonin *sputum *blood cultures (helpful if positive)
30
w/ HAP, there is a risk with _____
treating empirically- overtreating | start with broad spectrum then narrow based on culture results (risk of bug resistance in hospital)
31
when did we see flu assosciated pnumonaie and who did it effect?
young healthy people 2008: very severe mortality from flu-->MRSA-->pneumonae 2014: --> strep pneumoniae
32
index of suspicion of post-flu pneumonia is elevated by...
Hx of skin infection, recent flu, multilobar disease, lack of txt response, no flu vaccine
33
SARS and MERS cause by what virus?
mutated coronavirus - very high mortality
34
what is the most common opportunistic infection in HIV?
pneumocystitis jiroveci
35
low CD4 counts mean what?
low immune system (HIV pts have this)
36
many AIDs pts receive prophylactic azithromycin until their CD4 counts are up to avoid what kind of pneumonia?
mycobacterium (fungal)
37
most common types of mycobacterium pneumoniae
histoplasmosis- midwest from bird droppings | occidiomycosis- southwest
38
old people have less or more severe signs and symptoms of infection
less- dont mount immune response as well. Be wary of old people whose vitals are bad- this means the infection must be really bad.
39
major clinical presentation in elderly with pneumonia
tachypnea
40
what is BOOP?
bronchial obliterans organizing pneumoniae : bronchial and alveolar fibrous plugging --> looks like pneumonia but isnt infectious
41
etiology of BOOP
immune hypersensitivity and resulting fibrosis
42
txt for BOOP
steroids - but hard to taper off b/c signs recur once you start lowering