mood disorders Flashcards
etiology of major depression
no clear cause, its complex and multifactorial
are mood disorders more common in males or females?
females
4 types of mood disorders
Major Depressive Disorder (MDD)
Persistent Depressive Disorder
Premenstrual Dysphoric Disorder (PMDD)
Bipolar Disorder
3 types of bipolar disorder
Bipolar I Disorder
Bipolar II Disorder
Cyclothymic Disorder
what age group is most likely to have major depression?
baby boomers
what is anhedonia?
don’t enjoy the things you usually enjoy
who is more likely to experience irritability with depression? men or women?
often men
once someone has a major depressive episode is it more likely they will have another?
YES!
changes in sleeping and eating with major depression
more about CHANGE IN BASELINE - sleep more or less, eat more or less
4 sources of misDx of major depression (4 reasons it may be ignored)
- its a Sign of “normal” aging in elderly
- Cognitive impairment in elderly often misdiagnosed as dementia
- “Normal” following stressful events
- Comorbid gen med condition that “causes” symptoms of depression may lead to discounting the depressive symptoms
what are the 4 categories of symptoms for major depressive disorder?
- Affective- irritable, angry, flat
- Cognitive triad
- Behavioral- poor hygeine, isolated self, etc.
- Physiological
what is the “cognitive triad” ?
Cognitive triad: self, outside world, future
confused easily, lack of self worth, etc.
define: major depressive disorder- single episode
- Presence of single major dep episode
- Not better accounted for by schizoaffective d/o
- There has never been a manic episode, mixed episode, or hypomanic episode (this would be bipolar disorder)
define: major depressive disorder- recurrent
Presence of two or more MDEs, at least 2 months apart
what are the 3 various “specifiers” for major depressive disorder single, recurrent ?
With peripartum onset, with seasonal pattern, with psychotic features among others
major depressive episode DSM 5 dx
Five or more of the following symptoms present during same 2 week period, and represent a change from previous functioning (must have 1 or 2).
- depressed mood
- diminished interest
- change in weight
- change in sleep
- pyschomotor agitation or retardation
- fatigue
- feeling worthless
- decreased ability to concentrate
- recurrent thoughts of death
for DSM5 Dx: Symptoms MUST cause clinically significant in _______ or _______ social, occupational, other areas of functioning
distress or impairment
for DSM 5 Dx: symptoms must NOT be caused by…
substance or general medical condition
what defines persistent depressive disorder?
like “major depression light”: lasts longer but symptoms aren’t as severe
-Depressed mood for MOST of the day, MORE DAYS than not, for at least 2 YEARS (1 yr for children & adolescents)
what is dysthymia?
another name for persistent depressive disorder
persistent depressive disorder: Never without symptoms for more than____ at a time
2 months
what is premenstrual dysmorphic disorder?
at least 5 key symptoms present in the final week before menses. They improve after onset of menses, and gone the week after menses.
what is lability?
rapidly changing emotions
occurs with premenstrual dysmorphic disorder
major depression - must be around for how long? what about persistent depressive disorder?
major- 2 weeks
persistent- 2 years
some people with depression may present only with what type of symptoms?
physical
i.e. HA, backache, insomnia, dizzy, etc.
what is somatic symptom disorder?
physical symptoms without physiological basis that can look like depression but isnt
is txt for depression effective?
yes! 70-90%
3 types of pharmacotherapy for depression?
- Antidepressants for MDD, Dysthymia
SSRI (selective serotonin reuptake inhibitor) - Other first-line agents (Wellbutrin, Remeron, Serzone, Effexor)
- Tricyclics (side effects, overdose potential)
what is the most effective txt for depression?
cognitive behavioral therapy
(but works best in combo with meds)
what are the types of procedural txt for depression?
ECT, vagus nerve stimulation, light therapy
what is ECT?
anesthetized with an intravenous injection of a barbiturate or other anesthetic
-An electrical current is then passed through the brain, inducing a grand mal seizure
what is ECT and vagus stim. used for?
treatment-resistant depression
what is light therapy used for?
seasonal depression
bipolar 1 and 2 include different combos of three types of episodes
major depressive
manic
hypomanic
what defines a manic episode?
Distinct period of abnormally and persistently elevated, expansive, or irritable mood, and persistently increased goal-directed activity or energy (AT LEAST 1 WEEK)
Dx of manic episode, must have 3 or more of the following symptoms… AND notable change from previous behavior
- inflated self esteem
- decr. need for sleep
- talkative
- flight of ideas
- distractible
- goal-directed activity OR pyschomotor agitation
- dangerous activities (potential for painful consequence)
what defines a hypomanic episode?
Present for at least 4 days
- Must be a change from usual behavior
- DOES NOT CAUSE marked impairment in social or occupational functioning,
what defines bipolar 1 disorder
Must have at least 1 Manic Episode
May have Major Depressive Episodes
May have Hypomanic Episodes
what defines bipolar 2 disorder
Recurrent Major Depressive Episodes with Hypomanic Episodes
has never been a Manic Episode
what is the most over-diagnosed pysch disorder?
bipolar disorder
avg age of onset for bipolar disorder
20-30 yo.
bipolar disorders are what type of disorders ? (acute or chronic)
chronic
what is cyclothymic disorder?
Hypomanic symptoms (don’t meet criteria for hypomanic episode) AND depressive symptoms (don’t meet criteria for MDE) for at least 2 years
4 common specifiers for cyclothymic disorder
- with rapid cycling (4 episodes in a year)
- with psychotic features (delusion, hallucination)
- with anxious distress
- with seasonal pattern
3 types of psychopharmacology for bipolar disorder
- Mood stabilizers
- Anticonvulsant medications if don’t respond to mood stabilizers
- Antipsychotics if psychotic symptoms present
2 types of pyschotherapy txt for bipolar disorder
Usually cognitive-behavioral
Family therapy
why do men often have more successful suicide attempts?
they use guns or other more lethal methods
men or women attempt suicide more?
women
successful suicide without ____ or _____ is rare
alcohol/drug use
when is suicide at highest risk?
right after starting treatment- you get enough clarity in thinking to begin making a plan
5 parts of assessing lethality of suicide attempt
Plan Time period Method (and availability) Prior attempts Substance abuse
Bipolar II disorder is characterized by recurrent Major Depressive episodes with ___________ episodes.
hypomanic
Bipolar I disorder is characterized by recurrent Major Depressive episodes with ___________ episodes.
manic
Feelings of depression and hopelessness fall into which category of depressive symptoms?
affect
affect is the feelings as cognitive is to _____
thoughts