Pneumocystis Flashcards
Pneumocystis
Acquired thru contact of infected host and thru an
Airborne stage of the parasite
Pneumocystis
Found in human and rats are distinctly different from each other, are basically the same life cycle
P. Carini
Pneumocystis
Repdroduced by
Endodyogeny
Pneumocystis
P. Carinii in 2 forms
Trophozoites
Cysts
P. Carnii
Produce interstitial
Plasma cell pneumonia
Both form are found in
Pulmonary alveoli
Pneumocystis
Suspended in the matrix showing
Honeycomb
P. Carnii
Life cycle involves
Asexual reprduction of free trophozoites
P. Carnii
Effect of honeycomb
Emphysema
Pneumocystis
Sometimes occur
Mediastinal emphysema and pneumothorax
P. Carnii
Diagnosis
Specimen from ordinary cough
Cell culture
Gomoris
Gomoris methamenamics Ag stain, HE stain, for quick staining do
Toluidine blue
Most sensitive test
Immunifluorescence T
Treatment
Trimethoprim = 20 mg/kg/bw in 4 divided dose x 14 days
Alternative drug
Pentamidine 4 mg/kg/bw IM x 12-14 days