Parasitic Amoebas Flashcards

0
Q

More easily destroyed than the cyst

A

Trophozoite

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1
Q

Active vegatative form

15-30 u

A

Trophozoite

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2
Q

Ectoplasm of tropozoite is sharply separated from the

A

Endoplasm

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3
Q

Endoplasm of tropozoite sometimes include ____

A

RBC

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4
Q

How many nucleus tropozoite has?

A

1

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5
Q

Location of nucleus of tropozoite?

A

Eccenteric

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6
Q

Single eccenteric nucleus contains a _______ located _______

A

Centrally

Karyosome

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7
Q

Look like of tropozoite

A

Finger like pseudopodia

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8
Q

Tropozoite only has one?

A

Nucleus

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9
Q

What is the shape of the cyst

A

Round to oval

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10
Q

What is the size of cyst?

A

10-20 u

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11
Q

How many days the cyst can surive at 37c

A

2days

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12
Q

Cyst can survive 60 days at what temperature?

A

0C

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13
Q

Cyst has a _____ wall

A

Smooth refractile

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14
Q

Cytoplasm of cyst contains ____ and ____ for nutrition

A

Glycogen

Chomotoid bodies

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15
Q

Immature cyst

A

1 or 2 nuclei

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16
Q

Mature cyst

A

Infective

Contains 4 nuclei

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17
Q

Reproduction of trophozoite

A

Binary fission

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18
Q

Cyst- small intestine enzymes undergo ______ becomes ______

A

Exestation

Trophozoite

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19
Q

Cyst passes through _____

A

Stomach

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20
Q

How many trophozoites in the colon have?

A

8

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21
Q

Cyst formation

A

Encystation

Pt. only forms formed stools

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22
Q

Lesions under microscope, primary.

A

Intestinal

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23
Q

Lesions under microscope, secondary.

A

Extra intestinal

Liver

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24
Q

Colonization of the large intestine

A

Flask shaped ulcers
Wide base and narrow opening
Irregular slightly elevated
Muscularis propria

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25
Q

Complications

A
Appendicitis
Intestinal perforartion
Hemorrhage
Stricture
Granuloma (chronic)
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26
Q

Belong to a group of protozoans that are motile through cytoplasmic extensions known as pseudopods

A

Ameba

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27
Q

Example of amebas

A
Parasitic amebas
Entamoeba histolytica
E. coli
Dispar
Hartmanii
Gingivalis
Nana
Butchliii
28
Q

Entamoeba histolytica causes

A

Amebiasis
Amebic dysentery
Amebic hepatitis

29
Q

Principal host of E. histolytica

A

Human beings

30
Q

Example of E. H

A

Cyst

Trophozoite

31
Q

Cyst may be seen in

A

Formed stools

32
Q

Trophozoite commonly seen in

A

Diarrheic stools

33
Q

E.H incidence of infection is as high as

A

0.2 - 50%

34
Q

E.H prevalence in homos is as high as

A

25 - 35%

35
Q

Infective stage of organism

A

Cyst

36
Q

Main source of infection

A

Cyst

37
Q

Dissemination from the intestine chiefly by the bloodstream

A

Hepatic amoebiasis

38
Q

The wall of the abscess thickness and the center liquifies becoming a red brown mass of autolysed hepatic cells, rbc, bile, etc.

A

Hepatic amebiasis

39
Q

Extraintestinal

A

Hepatic amebiasis
Pulmonary amebiasis
Cerebral amebiasis

40
Q

How to diagnose?

A

Microspcopic identification of the cysts or trophozoites in feces or tissue

41
Q

What are components of amebic stools?

A

Acidic
Few neutrophils
Degenerated RBCs
Positive charcot leyden crytals ( derived from eosinophils )

42
Q

Treatment for parasitic amoebas

A

Metronidazole 750 mg TID for 5-10 days

Iodoquinol 650mg TID, 20 days

43
Q

Non pathogenic amoebas

A
Entamoeba coli
Entamoeba dispar
Entamoeba hartmanii
Entamoeba gungivalis
Entamoeba nana
Iodamoeba butchilii
44
Q

Prevalence of 10-30 %

A

E coli

45
Q

Life cycle to E H

Mistaken for a EH

A

E coli

46
Q

More ganular endoplasm containing ingested bacteria

A

E coli trophozoite

47
Q

Larger with more granular cytoplasm

A

E coli cyst

48
Q

In 1993, proposed as the name for non pathogenic E Histolytica

A

E dispar

49
Q

Originally though to be a “ small race” of EH, now considered as a seperate species

A

E hartmanii

50
Q

Narrower ectoplasm

A

E coli trophozoite

51
Q

Slender, splinter like chromatoid bodies neclei with eccenteric karyosome

A

E coli cyst

52
Q

Broader or blunter pseudopodia -

A

E coli trophozoite

53
Q

Identical to E H but does not invade the tissues

A

E dispar

54
Q

Eccenteric karyosome in the nucleus

A

E coli trophozoite

55
Q

More sluggish movement

A

E coli trophozoite

56
Q

Morphology is similar to E histolytica but smaller (12-15u)

A

E hartmanii

57
Q

Most stricking characteristics

A

E gingivalis

58
Q

10-20% prevalence

A

Endolimax nana

59
Q

With prominent karyosine

A

Endolimax nana

60
Q

Identified by the charac nucleus and large glycogen body in the uninucleated cyst

A

Iodamoeba buthclii

61
Q

Small (5-14)

A

Endolimax nana

62
Q

4 nucleus cyst, uninucleated trophozoite

A

Endolimax nana

63
Q

May be stained by iodine due to glycogen

A

Iodamoeba butchlii

64
Q

Blastocystis hominis

A

Yeast to protozoa

Large number found in feces with severe diarrhea

65
Q

Commonly in stool small

A

Blastocystis hominis

66
Q

Tereatment to blastocystis hominis

A

Metronidazole

67
Q

Appear in the feces as spherical cyst like stage large central vacuole with narrow rim of cytoplasm containing nuclei

A

Blastocystis hominis