Plasmodium and Malaria Flashcards

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1
Q

What THREE scientists won the 2015 Nobel Prize for Medicine for their work into Malaria?

A
  1. Tu Youyou
  2. William Campbell
  3. Satoshi Omura
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2
Q

What anti-malarial drug did Tu Youyou develop?

A

Artemisinin

From the Sweet Wormwood (Artemisia annua) plant

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3
Q

How many global cases of Malaria are there per year?

A

Approx. 200 million

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4
Q

How many people die from Malaria per year?

A

Between 400,000 and 500,000

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5
Q

What parasite causes Malaria?

A

Plasmodium falciparum

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6
Q

What type of parasite is Plasmodium falciparum?

A

Protozoal parasite

Apicomplexa

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7
Q

Who came up with the Endosymbiont Theory?

A

Lynn Margullis (1967)

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8
Q

What event gave rise to the origin of Apicomplexa?

A

Secondary endosymbiosis.

Where one algae cell was engulfed by a secondary host.

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9
Q

What is one of the key targets for anti-malarial drugs?

A

Apicoplasts

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10
Q

What TWO major parasites cause Malaria in humans?

A
  1. Plasmodium falciparum
  2. Plasmodium vivax
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11
Q

What mosquito species is most associated with spreading Malaria?

A

Anopheles gambiae

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12
Q

What has been the most effective way at controlling the spread of Malaria?

A

Insect repellent treated mosquito nets

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13
Q

What bacteria produce limburger volatiles that attract mosquitos?

A

Brevibacterium

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