Discovery of Streptomycin Flashcards

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1
Q

Which TWO people are generally credited with the discovery of Streptomycin?

A
  1. Selman Waksman
  2. Albert Schatz
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2
Q

DEFINE:

Antibiotic

A

A class of drugs used to treat bacterial infections

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3
Q

DEFINE:

Antibacterial

A

Used to be a synonym for antibiotics

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4
Q

DEFINE:

Antifungal

A

A class of drugs used to treat fungal infections

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5
Q

DEFINE:

Antiviral

A

A class of drugs used to treat viral infections

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6
Q

DEFINE:

Antimicrobial

A

An umbrella term for antibiotics, antibacterial, anti fungal, and antiviral substances

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7
Q

What TWO soil actinomycetes were the first bacteria found to produce Streptomycin?

A
  1. Streptomyces griseus 18-16
  2. Streptomyces griseus D1
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8
Q

What bacterium was Streptomycin first tested on?

A

Mycobacterium tuberculosis

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9
Q

How does Streptomycin work?

A

Inhibit protein synthesis in a cell

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10
Q

What are some examples of NARROW SPECTRUM antibiotics?

A
  1. Isoniazid
  2. Polymyxins
  3. Vancomycin
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11
Q

What is an example of a BROAD SPECTRUM antibiotic?

A

Tetracycline

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12
Q

What classes of antibiotics target CELL WALL SYNTHESIS?

A
  1. Penicillin
  2. Cephalosporins
  3. Vancomycin
  4. Bacitracin
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13
Q

What classes of antibiotics target PROTEIN SYNTHESIS?

A
  1. Streptomycin
  2. Tetracyclines
  3. Erythromycin
  4. Chloramphenicol
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14
Q

What classes of antibiotics target NUCLEIC ACID REPLICATION and TRANSCRIPTION?

A
  1. Quinolones
  2. Rifampin
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15
Q

What classes of antibiotics target SYNTHESIS OF ESSENTIAL METABOLITES?

A
  1. Sulfanilamide
  2. Trimethoprim
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16
Q

What umbrella term do Penicillins and Cephalosporins fall under?

A

Beta-Lactams