Antibiotic Resistance

Question 1

What are some mechanisms of antibiotic resistance?

Answer 1

1. Prevent the antibiotic from reaching its target
2. Prevent the antibiotic from binding to its target
3. Inactivation before reaching the target

Question 2

What mechanism of resistance applies most to Penicillin?

Answer 2

Inactivation before reaching the target

Question 3

How does the production of Penicillinase give bacteria resistance to Penicillin?

Answer 3

By cleaving the Beta-Lactam ring to form Penicilloic Acid

Question 4

What strategies are used to counter resistance to Beta-Lactam antibiotics?

Answer 4

1. Penicillinase-resistant penicillins
2. Beta-Lactamase inhibitors

Question 5

What semisynthetic antibiotic is resistant to penicillinase?

Answer 5

Oxacillins

Question 6

Name a Beta-Lactamase (Penicillinase) inhibitor?

Answer 6

Clavulanic acid

Question 7

What class of antibiotic is Beta-Lactamase resistant?

Answer 7

Carbapenems

Question 8

What THREE interactions make up the One Health concept for tackling antimicrobial resistance (AMR)?

Answer 8

1. Human Health
2. Animal Health
3. Environmental Health

Question 9

What UN sustainable development goals apply to the One Health concept for AMR?

Answer 9

1. No poverty
2. Zero hunger
3. Good health and wellbeing
4. Clean water and sanitation
5. Industry, innovation and infrastructure
6. Reduced inequalities
7. Responsible consumption and production
8. Partnerships for the goals