Coronavirus Flashcards
What is the name of the virus that causes COVID-19?
SARS-CoV-2
What type of virus is SARS-CoV-2?
- Enveloped
- ssRNA(+)
What receptor on the host cell does SARS-CoV-2 bind to?
ACE2
Angiotensin II receptor
Name TWO potential drug targets to prevent the replication of SARS-CoV-2
- ACE2 receptors
- RNA-dependent RNA Polymerase
Which THREE Coronaviridae cause severe disease in humans?
- SARS-CoV-1
- SARS CoV-2
- MERS
Which FOUR Coronaviridae cause mild respiratory disease in humans?
- HKU1
- NL63
- OC43
- 229E
Which animal is the major reservoir of coronaviruses?
Bats
What THREE years had MERS outbreaks?
- 2014
- 2015
- 2019
In what animal reservoir did the Omicron variant of SARS-CoV-2 evolve in?
Rodents
What diagnostic test tests for current infection of SARS-CoV-2?
- PCR test (RNA)
- Antigen test (protein)
What test tests for past infection of SARS-CoV-2?
Antibody test (Immune Response)
Who is the scientist credited with the development of mRNA vaccines?
Katalin Karikó
How do you calculate the percentage of a population that needs to be vaccinated in order to achieve herd immunity?
(R0-1)/R0