Coronavirus Flashcards

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1
Q

What is the name of the virus that causes COVID-19?

A

SARS-CoV-2

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2
Q

What type of virus is SARS-CoV-2?

A
  • Enveloped
  • ssRNA(+)
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3
Q

What receptor on the host cell does SARS-CoV-2 bind to?

A

ACE2

Angiotensin II receptor

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4
Q

Name TWO potential drug targets to prevent the replication of SARS-CoV-2

A
  1. ACE2 receptors
  2. RNA-dependent RNA Polymerase
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5
Q

Which THREE Coronaviridae cause severe disease in humans?

A
  1. SARS-CoV-1
  2. SARS CoV-2
  3. MERS
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6
Q

Which FOUR Coronaviridae cause mild respiratory disease in humans?

A
  1. HKU1
  2. NL63
  3. OC43
  4. 229E
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7
Q

Which animal is the major reservoir of coronaviruses?

A

Bats

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8
Q

What THREE years had MERS outbreaks?

A
  • 2014
  • 2015
  • 2019
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9
Q

In what animal reservoir did the Omicron variant of SARS-CoV-2 evolve in?

A

Rodents

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10
Q

What diagnostic test tests for current infection of SARS-CoV-2?

A
  • PCR test (RNA)
  • Antigen test (protein)
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11
Q

What test tests for past infection of SARS-CoV-2?

A

Antibody test (Immune Response)

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12
Q

Who is the scientist credited with the development of mRNA vaccines?

A

Katalin Karikó

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13
Q

How do you calculate the percentage of a population that needs to be vaccinated in order to achieve herd immunity?

A

(R0-1)/R0

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